Abstract
Brain tumors are the most common solid tumor of childhood and remain the leading cause of cancer-related mortality in children. Advances in diagnostic techniques, neurosurgical procedures, radiotherapy, and chemotherapeutic regimens have resulted in modest improvements in survival; however, outcomes remain suboptimal and morbidity frequent. Increased understanding of the underlying molecular characteristics of brain tumors in children has led to the design and early testing of targeted agents, although continued investigation is needed. This chapter will serve as a general introduction to the principles of diagnosis and treatment in children with brain tumors, and will apply those principles in a brief overview of the most common tumors.
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Hwang, E.I., Packer, R.J. (2012). Pediatric Brain Tumors (An Overview). In: Hayat, M. (eds) Pediatric Cancer, Volume 2. Pediatric Cancer, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2957-5_7
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DOI: https://doi.org/10.1007/978-94-007-2957-5_7
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