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Pluripotent Human Stem Cells: An Overview

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Stem Cells and Cancer Stem Cells, Volume 1

Part of the book series: Stem Cells and Cancer Stem Cells ((STEM,volume 1))

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Abstract

For the past few years, cell therapy with pluripotent stem cells has been central to the prospect of regenerative medicine. From the traditional human embryonic stem cell (HSC) to the more recent induced pluripotent stem cells (iPSC), the main objective across all is to make use of the property of cell pluripotency to generate target cell types for therapeutic purposes. This chapter reviews some aspects of pluripotency in human cells, including its characteristics and regulatory factors, as well as various cell-reprogramming and single-cell analysis techniques developed for the manipulation of pluripotency in human cells and the clinical aspects of current methods.

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Acknowledgments

This work was supported by a grant from National Science Foundation (AW# 0852720).

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Authors and Affiliations

  1. Department of Pathology, University of Southern California, Los Angeles, CA, 90033, USA

    Gina Y. Chen & Jiang F. Zhong

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  1. Gina Y. Chen
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  2. Jiang F. Zhong
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Correspondence to Jiang F. Zhong .

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Editors and Affiliations

  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Chen, G.Y., Zhong, J.F. (2012). Pluripotent Human Stem Cells: An Overview. In: Hayat, M. (eds) Stem Cells and Cancer Stem Cells, Volume 1. Stem Cells and Cancer Stem Cells, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1709-1_1

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