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Abstract

Just like equivalence studies noninferiority studies are very popular in modern clinical research with many treatments at hand and new compounds being mostly only slightly different from the old ones. Unlike equivalence studies (Chap. 6), noninferiority studies have a single boundary, instead of two boundaries, with an interval of equivalence in between. Noninferiority studies have been criticized for their wide margin of inferiority making it virtually impossible to reject noninferiority.

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Correspondence to Ton J. Cleophas .

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© 2011 Springer Science+Business Media B.V.

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Cleophas, T.J., Zwinderman, A.H. (2011). Noninferiority Testing. In: Statistical Analysis of Clinical Data on a Pocket Calculator. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1211-9_9

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