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Applications: Nanobiosystems, Medicine, and Health

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Nanotechnology Research Directions for Societal Needs in 2020

Part of the book series: Science Policy Reports ((SCIPOLICY,volume 1))

Abstract

Over the past decade, nanomedicine and nanobiology have undergone radical transformations from fantasy to real science. The days of discussing advances in this area in the context of “nanobots” are over, and systems and nanomaterials have emerged that provide major analytical or therapeutic advantages over conventional molecule-based structures and approaches. We have come to recognize that much of biology is executed at the nanoscale level, therefore providing a rational approach to using the structure and function of engineered nanomaterials at the nano-bio interface for interrogation of disease, diagnosis, treatment, and imaging at levels of sophistication not possible before [1]. Fabrication of a host of nanostructures has been coupled with advanced chemical manipulation in order to impart biological recognition and interaction capabilities. Often, chemical manipulation results in nanomaterials that provide performance enhancement of therapeutics, imaging agents, diagnostics, and materials for tissue engineering and for basic science applications.

*  With contributions from: Barbara A. Baird, Carl Batt, David Grainger, Sanjiv Sam Gambhir, Demir Akin, Otto Zhou, J. Fraser Stoddart, Thomas J. Meade, Piotr Grodzinski, Dorothy Farrell, Harry F. Tibbals, Joseph De Simone.

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Notes

  1. 1.

    PSA is a serum biomarker used to screen individuals for prostate cancer and also as a marker for prostate cancer recurrence following primary and secondary prostate cancer intervention [32].

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Authors and Affiliations

  1. Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208, USA

    Chad A. Mirkin

  2. Department of Medicine and California NanoSystems Institute, University of California, 10833 Le Conte Avenue, 52-175 CHS, Los Angeles, CA, 90095, USA

    André Nel

  3. Institute for Bionanotechnology in Medicine, Northwestern University, Robert H. Lurie Building, 303 E Superior Street, Room 10-250, Chicago, IL, 60611, USA

    C. Shad Thaxton

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  1. Chad A. Mirkin
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Correspondence to Chad A. Mirkin .

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Mirkin, C.A., Nel, A., Thaxton, C.S. (2011). Applications: Nanobiosystems, Medicine, and Health. In: Nanotechnology Research Directions for Societal Needs in 2020. Science Policy Reports, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1168-6_8

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