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Clear Cell Carcinoma of the Ovary: Prognosis Using Cytoreductive Surgery

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Methods of Cancer Diagnosis, Therapy, and Prognosis

Part of the book series: Methods of Cancer Diagnosis, Therapy and Prognosis ((HAYAT,volume 6))

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Abstract

Clear cell carcinoma of the ovary was initially termed as “mesonerhroma ovarii” by Schiller (1939), as the tumor resembled renal cell carcinoma and was believed to originate from mesonephric structure. Approximately, three decades ago, it was strictly defined by the World Health Organization classification of ovarian tumors (Serov et al. 1973) as lesions characterized by clear cells growing in solid/tubular or glandular patterns as well as hobnail cells. Recently, many publications have identified the distinctive clinical behavior of clear cell carcinoma; resistance to platinum-based chemotherapy (Omura et al. 1991) and poor prognosis in comparison with other histologic subtypes (Sugiyama et al. 2000; Pectasides et al. 2006). The distinguished characteristics of clear cell carcinoma are described in this chapter: clinical and molecular characteristics of the tumor and prognosis after comprehensive cytoreductive surgery.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan

    Masashi Takano, Naoki Sasaki & Toru Sugiyama

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  1. Masashi Takano
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  2. Naoki Sasaki
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  3. Toru Sugiyama
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Editors and Affiliations

  1. Dept. Biological Sciences, Kean University, Union, 07083, U.S.A.

    M. A. Hayat

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Takano, M., Sasaki, N., Sugiyama, T. (2010). Clear Cell Carcinoma of the Ovary: Prognosis Using Cytoreductive Surgery. In: Hayat, M. (eds) Methods of Cancer Diagnosis, Therapy, and Prognosis. Methods of Cancer Diagnosis, Therapy and Prognosis, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2918-8_7

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  • DOI: https://doi.org/10.1007/978-90-481-2918-8_7

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