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Application Efficiency of Complex Preparations Based on Nanodisperse Silica in Medical Practice

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Nanomaterials and Supramolecular Structures

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Abstract

Unique physical–chemical properties of amorphous silica surface provide certain biological effects: high hydrophilia, affinity to proteins, adsorption of microorganisms and of some low-molecular substances. All of them, as well as the capability of amorphous silica to modulate pharmacokinetics and biotransformation of other medicines by joint administration, allow us to use it not only as a medication of applicational and oral therapy, but also as a matrix or a carrier to create combined drugs. A number of such perspective medical products as Aquasil, Siloglucan, Phytosilard, Lysosil, Lysetox, Flotoxan are now at different stages of development, preclinical, and clinical studies.

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Authors and Affiliations

  1. Institute of Surface Chemistry of the National Academy of Sciences of Ukraine, General Naumov St. 17, 03164, Kyiv, Ukraine

    O.O. Chuiko, P.P. Gorbyk, V.K. Pogorelyi, A.A. Pentyuk, I.I. Gerashchenko, A.V. Il’chenko, E.I. Shtat’ko, N.B. Lutsyuk, A.A. Vil’tsanyuk, Y.P. Verbilovsky & O.I. Kutel’makh

Authors
  1. O.O. Chuiko
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  2. P.P. Gorbyk
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  3. V.K. Pogorelyi
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  4. A.A. Pentyuk
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  5. I.I. Gerashchenko
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  6. A.V. Il’chenko
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  7. E.I. Shtat’ko
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  8. N.B. Lutsyuk
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  9. A.A. Vil’tsanyuk
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  10. Y.P. Verbilovsky
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  11. O.I. Kutel’makh
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Editor information

Editors and Affiliations

  1. G.V. Kurdiumov Inst. Metal Physics, National Academy of Sciences of Ukraine, Blvd. Akademika Vernadskogo 36, Kiev, 03680, Ukraine

    Anatoliy Petrovych Shpak

  2. A. A. Chuiko Inst. Surface Chemistry, National Academy of Sciences of Ukraine, General Naumov St. 17, Kiev, 03164, Ukraine

    Petr Petrovych Gorbyk

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Chuiko, O. et al. (2009). Application Efficiency of Complex Preparations Based on Nanodisperse Silica in Medical Practice. In: Shpak, A., Gorbyk, P. (eds) Nanomaterials and Supramolecular Structures. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2309-4_5

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