Abstract
The discovery of incidental adrenal masses during imaging procedures has become progressively more frequent. In such situations a correct clinical and biochemical approach have to be performed in order to obtain information on the biological and functional nature of the adrenal mass. Clinicians are asked to establish whether the adrenal mass is an adenoma, a pheochromocytoma, an adrenal carcinoma or a metastasis, and to perform a correct laboratory evaluation to search for even mild derangements in adrenal secretion. Recognition of mild signs and symptoms related to slight adrenal hypersecretion may permit a precocious identification of diseases associated with significant morbidity and mortality. Indeed cardiovascular events represent the most frequent complications due to catecholamine release by a pheochromocytoma, or to chronic hypercortisolism as in Cushing’s syndrome. Finally, the early recognition of an adrenal carcinoma is of utmost importance to improve the outcome and the prognosis of this biologically aggressive tumor.
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Parenti, G., Mannelli, M. (2013). Diagnosis and Clinical Pictures. In: Valeri, A., Bergamini, C., Bellantone, R., Lombardi, C. (eds) Surgery of the Adrenal Gland. Springer, Milano. https://doi.org/10.1007/978-88-470-2586-8_4
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DOI: https://doi.org/10.1007/978-88-470-2586-8_4
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