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New Approach to Diagnosis and Prognosis

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Biotechnology in Surgery

Part of the book series: Updates in Surgery ((UPDATESSURG,volume 0))

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Abstract

Peritoneal carcinomatosis is the spreading of malignant cells into the peritoneal cavity. The peritoneal dissemination of cancer cells is the deposition of malignant cells onto parietal or visceral peritoneal surfaces, associated or less with the accumulation of malignant ascites. The ascites is rich in growth factors, bioactive lipids, extracellular matrix (ECM) components, inflammatory mediators, and proteolytic enzymes, creating a neoplastic microenvironment that fosters further metastatic spread. Primary peritoneal carcinomatosis is rare, whereas a secondary peritoneal carcinomatosis of ovarian (60% of ovarian cancer), gastric (40%) and colorectal cancer (15%) is frequently ob

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  1. Department of Medical and Surgical Critical Care, University of Florence and Regional Reference Centre of Tuscany for Locoregional Perfusion Therapies, Florence, Italy

    Paolo Bechi

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  1. Department of Anesthesiological, Surgical and Emergency Sciences, Second University of Naples, Naples, Italy

    Alfonso Barbarisi

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Bechi, P. (2011). New Approach to Diagnosis and Prognosis. In: Barbarisi, A. (eds) Biotechnology in Surgery. Updates in Surgery, vol 0. Springer, Milano. https://doi.org/10.1007/978-88-470-1658-3_2

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