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Preliminary Phytochemical and Antimicrobial Activity of Ethanolic Extract of Pittosporum viridulum Stem Bark

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Prospects in Bioscience: Addressing the Issues

Abstract

The ethanolic extract of Pittosporum viridulum stem bark was screened for antibacterial activity using disc diffusion method. The phytochemical analysis of the extract was also carried out to detect total phenolic content and total flavonoids. The ethanolic extract of P. viridulum showed a good antimicrobial activity against Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa and Klebsiella pneumoniae. Antibiotic chloramphenicol is used as positive control. Maximum zone of growth inhibition was observed against Pseudomonas aeruginosa, with an inhibition zone of 18 mm for ethanol extract. The extract used for screening was prepared by dissolving 1 and 2 mg/100 μl DMSO. Phytochemical screening of Pittosporum viridulum showed the presence of carbohydrates, glycosides, amino acids, fixed oils and fats, flavonoids, saponins and phenol.

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Correspondence to C. T. Sadashiva .

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Sadashiva, C.T., George, S., Balan, N., Kumar, U.P., Balachandran, I. (2012). Preliminary Phytochemical and Antimicrobial Activity of Ethanolic Extract of Pittosporum viridulum Stem Bark. In: Sabu, A., Augustine, A. (eds) Prospects in Bioscience: Addressing the Issues. Springer, India. https://doi.org/10.1007/978-81-322-0810-5_10

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