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Part of the book series: Allergy Frontiers ((ALLERGY,volume 5))

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Obviously, anaphylaxis is an unavoidable aspect of the practice of medicine. With the growing use of polypharmacy and the present epidemic of allergic disease, its incidence is increasing [1].

Although it is not possible to prevent all such episodes, some general preventive measures can reduce the frequency and severity of these events (Table 1).

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References

  1. Warner JO (1997) Anaphylaxis; the latest allergy epIDemic. Pediatr Allergy Immunol 18:1–2

    Article  Google Scholar 

  2. Lieberman P (2003) Use of epinephrine in treatment of anaphylaxis. Curr Opin Allergy Clin Immunol 3:313–318

    Article  CAS  PubMed  Google Scholar 

  3. Webb L, Lieberman P (2006) Anaphylaxis: a review of 601 cases. Ann Allergy Immunol 97:39–43

    Google Scholar 

  4. Lieberman P, Kemp SF, Oppenheimer J, Lang DM, Bernstein IL, Nicklas RA (2005) Letter reply. J Allergy Clin Immunol 116:933–936

    Article  Google Scholar 

  5. Lieberman P (2003) Anaphylaxis and anaphylactoID reactions. In: Allergy: Principles and Practice, edition 6, Adkinson F, Yunginger J, Busse W, Bochner B, Holgate S, Simons FER (eds) (Mosby, an affiliate of Elsevier, US) pp 1497–1522

    Google Scholar 

  6. Physicians Desk Reference (PDR) (2005) Thomson, page 1186

    Google Scholar 

  7. Physicians Desk Reference (PDR) (2005) Thomson, page 732

    Google Scholar 

  8. Mink SN, Simons FER, Simons KJ, et al. (2004) Constant infusion of epinephrine, but not bolus treatment, improves haemodynamic recovery in anaphylactic shock in dogs. Clin Exp Allergy 34(11):1776–1783

    Article  CAS  PubMed  Google Scholar 

  9. Gei A, Pachecho L, Van Hook J (2003) The use of continuous infusion of epinephrine for anaphylactic shock during labor. Obstet Gynecol 102:1332–1335

    Article  CAS  PubMed  Google Scholar 

  10. Brown SGA (2005) Cardiovascular aspects of anaphylaxis: implications for treatment and diagnosis. Curr Opin Allergy Clin Immunol 5:369–364

    Google Scholar 

  11. Lieberman P, Kemp S, Oppenheimer J, Lang D, Bernstein I, Nicklas R (2005) The diagnosis and management of anaphylaxis: an updated practice parameter. J Allergy Clin Immunol 115:S483–S523 (supplement)

    Article  Google Scholar 

  12. Brown SGA, Blackman KE, Stenlake V, Heddle RJ (2004) Insect sting anaphylaxis; prospective evaluation of treatment with intravenous adrenaline and volume resuscitation. Emerg Med J 21:149–154

    Article  CAS  PubMed  Google Scholar 

  13. Schummer W, Schummer C, Wippermann J (2004) Anaphylactic shock: is vasopressin the drug of choice? Anaest 101:1025–1027

    Article  Google Scholar 

  14. Wenzel V, Krismer AC, Arantz HR(2004) A comparison of vasopressin and epinephrine for out of hospital cardiopulmonary resuscitation. N Engl J Med 350:105–113

    Article  CAS  PubMed  Google Scholar 

  15. Stiell IG, Herbert PC, Wells GA (2001) Vasopressin versus epinephrine for in hospital cardiac arrest: a randomized controlled trial. Lancet 358:105–109

    Article  CAS  PubMed  Google Scholar 

  16. Sheth SS, Del Duca D, Ergina P, Clarke AE (2007) Methylene blue as a treatment for refractory anaphylaxis. J Allergy Clin Immunol

    Google Scholar 

  17. Lin RY, Curry A, Pesola G (2000) Improved outcomes in patients with acute allergic syndromes who are treated with combined H1 and H2 antagonists. Ann Emerg Med 36:462–468

    CAS  PubMed  Google Scholar 

  18. Ellis AK, Day JH (2007) IncIDence and characteristics of biphasic anaphylaxis: a perspective evaluation of 103 patients. Ann Allergy Asthma Immunol 98:64–69

    PubMed  Google Scholar 

  19. Lieberman P (2005) Biphasic anaphylactic reactions. Ann Allergy Asthma Immunol 95:217–226

    Article  PubMed  Google Scholar 

  20. Sicherer S, Simons EFR (2005) Quandaries in prescribing emergency action plans and self-injectable epinephrine for first-aID management of anaphylaxis in the community. J Allergy Clin Immunol 115:575–583

    Article  PubMed  Google Scholar 

  21. Simons FE, Gu X, Simons KJ (2001) Epinephrine absorption in adults: intramuscular versus subcutaneous injection. J Allergy Clin Immunol 108:871–873

    Article  CAS  PubMed  Google Scholar 

  22. Simons FER, Gu X, Simons KJ (2000) Outdated EpiPen and EpiPen Junior autoinjectors: past their prime? J Allergy Clin Immunol 105:1025–1030

    Article  CAS  PubMed  Google Scholar 

  23. Kelso JM (2006) A second dose of epinephrine for anaphylaxis: how often needed and how to carry. J Allergy Clin Immunol 117(2):464–465

    Article  PubMed  Google Scholar 

  24. Soar J, Deakin C, Nolen J (2005) European Resuscitation Council guIDelines for resuscitation 2005, Section 7. Cardiac arrest in special circumstances. Resuscitation 6751:S135–S170 (supplement).

    Article  Google Scholar 

  25. Pumphrey RSH (2004) Fatal anaphylaxis in the UK, 1992–2001. In: Anaphylaxis (publication of The Novartis Foundation, John Wiley & Sons Ltd, summary of Novartis Foundation Symposium 257, 2004. John Wiley & Sons Ltd, the Atrium, Southern Gate, Chichester, UK), pp 116–132

    Google Scholar 

  26. Pumphrey RSH, Gowland M (2007) Further fatal allergic reactions to food in the United Kingdom, 1999 2006. J Allergy Clin Immunol 19:1018

    Article  Google Scholar 

  27. Pumphrey RSH (2003) Fatal posture in anaphylactic shock. J Allergy Clin Immunol 112:451– 452 (Letter to Editor)

    PubMed  Google Scholar 

  28. Rotskoff BD, Greenberger PA, Lifschultz B (2003) Fatal anaphylaxis: postmortem findings and associated comorbID disease. J Allergy Clin Immunol 111:S101 (abstract)

    Article  Google Scholar 

  29. Bock SA, Munoz-Furlong A, Sampson HH (2007) Further fatalities caused by anaphylactic reactions to food, 2001–2006. J Allergy Clin Immunol 119:1016–1018

    Article  PubMed  Google Scholar 

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Lieberman, P. (2009). Management of Anaphylaxis. In: Pawankar, R., Holgate, S.T., Rosenwasser, L.J. (eds) Allergy Frontiers: Therapy and Prevention. Allergy Frontiers, vol 5. Springer, Tokyo. https://doi.org/10.1007/978-4-431-99362-9_18

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  • DOI: https://doi.org/10.1007/978-4-431-99362-9_18

  • Publisher Name: Springer, Tokyo

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