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Immunosuppressants as Treatment for Atopic Dermatitis

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Allergy Frontiers: Therapy and Prevention

Part of the book series: Allergy Frontiers ((ALLERGY,volume 5))

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Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting about 20% of children and up to 3% of adults worldwide. The clinical manifestation of AD is based on the interaction of specific genetic predispositions with a large number of environmental factors. Treatment of AD depends on the course and severity of the disease as well as the most important trigger factors such as aero- or foodallergens, microbial pathogens or other exogenous and endogenous influences [1]. Here we provide an overview of the mode of action of different immunosuppressants, which are frequently used as treatment for AD.

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Authors and Affiliations

  1. Department of Dermatology, Medical University of Warsaw, Warsaw, Poland

    Bartlomiej Kwiek

  2. Department of Dermatology and Allergy, University of Bonn, Sigmund-Freud-Strasse 25, Bonn, 53105, Germany

    Natalija Novak

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  1. Bartlomiej Kwiek
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  2. Natalija Novak
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  1. Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan

    Ruby Pawankar

  2. University of Southampton Southampton General Hospital, Tremona Road, Southampton, UK

    Stephen T. Holgate

  3. Children's Mercy Hospitals and Clinics UMKC School of Medicine, 2401 Gillham Road, Kansas City, MO, 64108, USA

    Lanny J. Rosenwasser

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Kwiek, B., Novak, N. (2009). Immunosuppressants as Treatment for Atopic Dermatitis. In: Pawankar, R., Holgate, S.T., Rosenwasser, L.J. (eds) Allergy Frontiers: Therapy and Prevention. Allergy Frontiers, vol 5. Springer, Tokyo. https://doi.org/10.1007/978-4-431-99362-9_17

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