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Potential impact of rotavirus vaccination on the mortality of children in developing countries

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Pediatric Infectious Diseases Revisited

Part of the book series: Birkhäuser Advances in Infectious Diseases ((BAID))

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Abstract

The global burden of rotavirus infection and associated mortality in infants and young children has led to the international prioritization of the development of a rotavirus vaccine. In recent months, two new rotavirus vaccines have been licensed by the multinational pharmaceutical industry and are currently being introduced into routine childhood immunization schedules in the Americas and Europe. However, for the full impact of these rotavirus vaccines to be felt they need to be introduced into Africa and Asia where the bulk of rotavirus associated mortality occurs. Several questions regarding the efficacy of the vaccines in these settings remain, as well as questions of supply and pricing of the vaccines.

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Authors and Affiliations

  1. Initiative for Vaccine Research, Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland

    Duncan Steele

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  1. Duncan Steele
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  1. Pediatric Infectious Diseases Department of General Pediatrics, University Children’s Hospital, Moorenstr. 5, 40225, Düsseldorf, Germany

    Horst Schroten

  2. Children’s Hospital HELIOS Klinikum, Witten-Herdecke University, Heusnerstr. 40, 42283, Wuppertal, Germany

    Stefan Wirth

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Steele, D. (2007). Potential impact of rotavirus vaccination on the mortality of children in developing countries. In: Schroten, H., Wirth, S. (eds) Pediatric Infectious Diseases Revisited. Birkhäuser Advances in Infectious Diseases. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8099-1_2

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