Zusammenfassung
Die Sepsis geht in der Regel mit einer Anzahl von metabolischen Störungen einher: Erhöhte Plasmalaktatkonzentration, metabolische Azidose, verstärkte Glykolyse und ein abnormer „transportabhängiger“ Sauerstoffverbrauch. Es bestehen heute zwei Hypothesen zur Erklärung dieser Veränderungen:
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a)
Die zelluläre Hypoxie resultiert aus einer pathologisch veränderten Mikrozirkulation.
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b)
Es besteht eine primäre Störung im zellulären Energiestoffwechsel.
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© 1994 Springer-Verlag/Wien
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Hotchkiss, R.S. (1994). Pathophysiologie der Azidose bei Sepsis. In: Kleinberger, G., Lenz, K., Ritz, R., Schneeweiß, B., Schuster, HP., Waldhäusl, W. (eds) Metabolismus. Intensivmedizinisches Seminar, vol 7. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9342-6_6
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DOI: https://doi.org/10.1007/978-3-7091-9342-6_6
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