Summary
Animal experiments were performed to restore bony defects with morsellized allograft chips. Acetabular defects were created in the Dutch milk goat and impacted with fresh frozen allograft bone chips. The speed of consolidation with the host bone bed, the mechanism and completeness of incorporation and the processes at the graft cement interface were studied in detail with histological and biomechanical procedures.
Histology showed that the graft had consolidated with the trabecular host bone bed within three weeks. In the subsequent period a front of vascular sprouts infiltrated the graft. Graft resorption, new bone formation and bone remodelling resulted in a new trabecular structure with optimal trabecular orientation for load bearing. After twelve weeks only scarce remnants of the original dead graft material remained in the incorporated area of the graft. At revascularized areas of the graft-cement interface, graft resorption and new bone formation had resulted in direct vital bone-cement contact sites and in areas with a soft tissue interface. After longer follow-up periods progressive interface formation and loosening of the cup was found in most of the animals.
The histological results were confirmed by biomechanical stability tests. In the first postoperative weeks the stability of the reconstruction increased, but at later follow-up periods, interface formation at the new bone-cement layer compromised the stability of the reconstruction.
The results indicated that reconstruction with morsellized graft material leads to rapid consolidation, incorporation and remodelling of the graft. Problems at the graft-cement interface are probably not related to the use of the morsellized graft, but to the goat model used.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Albee FH (1923) Fundamentals in bone transplantation. Experiences in three thousand bone grafts. J Am Med Assn 81: 1429 – 1432
Albee FH (1912) Discussion of the preservation of tissues and its application in surgery. J Am Med Assn 59: 527
Axhausen G (1911) Arbeiten aus dem Gebiet der Knochenpathologie und Knochenchirurgie.l. Kritische Bemerkungen und neue Beitrage zur freien Knochentransplantation. Arch Klin Chir 94: 241 – 281
Barth A (1908) Ueber Osteoplastik. Arch Klin Chir 86: 859 – 872
Brooks DB, et al (1963) Immunological factors in homogenous bone transplantation. IV. The effect of various methods of preparation and irradiation on antigenicity. J Bone Joint Surg 45-A: 1617 – 1625
Buma P, Schreurs BW, Versleyen D, Huiskes R, Slooff TJ (1992) Histologic evaluation of allograft incorporation after cemented and non-cemented hip arthroplasty in the goat. In: Older J (ed) Bone implant grafting. London: Springer, 12
Burchardt H, Busbee OA, Enneking WF (1975) Repair of experimental autologous grafts of cortical bone. J Bone Joint Surg 57-A: 814
Burchardt H (1989) Biology of cortical bone graft incorporation. In: Aebi M, Regazzoni P (eds) Bone transplantation. Berlin: Springer, pp 23 – 29
Burwell RG, Gowland G (1962) Studies in the transplantation of bone. The immune response of lymph nodes draining components of fresh homogenous bone treated by different methods. J Bone Joint Surg 44-B: 131 – 148
Burwell RG (1969) The fate of bone grafts. In: Apley GA (ed) Recent advances in orthopaedics. London: Churchill, pp 115 – 207
Bush LF (1947) The use of homogenous bone grafts. A preliminary report on the bone bank. J Bone Joint Surg 29: 620 – 628
Campbell CJ (1953) Experimental study of the fate of bone grafts. J Bone Joint Surg 35-A: 332 – 346
Curtis BF (1892) Bone transplantation for nonunited fractures. Medical Record, Jan 2
Enneking WF, Mindell ER (1991) Observation on massive retrieved human allografts. J Bone Joint Surg 73-A: 1123 – 1142
Friedlaender GE (1991) Bone allografts: the biological consequences of immunological events. J Bone Joint Surg 73-A: 1119 – 1123
Friedlaender GE (1987) Current concepts review on bone grafts. The basic science rationale for clinical applications. J Bone Joint Surg 69-A: 780
Goldberg VM, Powell A, Shaffer JW, Zika J, Stevenson S, Davy D, Heiple K (1989) The role of histocompatibility in bone allografting. In: Aebi M, Regazzoni P (eds) Bone transplantation. Berlin: Springer, 126
Goldberg VM, Stevenson S (1987) Natural history of autografts and allografts. Clin Orthop 225: 7
Greco F, De Palma U, Spechia A, Santucci A (1989) Biological aspects of repair osteogenesis in cortico-spongy homologous grafts. Ital J Orthop Traumatol 23: 491
Harris WH, Crothers O, Oh I (1977) Total hip replacement and femoral head bone grafting for severe acetabular deficiency in adults. J Bone Joint Surg 59-A: 752
Hastings DE, Parker SM (1975) Protrusio acetabula in rheumatoid arthritis. Clin Orthop 108: 7684
Heiple KG, Chase SW, Herndon CH (1963) A comparative study of the healing process following different types of bone transplantation. J Bone Joint Surg 45-A: 1593 – 1612
Herndon CH, Chase SW (1954) The fate of massive autogenous and homogenous bone grafts including articular surfaces. Surg Gynec Obstet 98: 273 – 290
Lexer E (1908) Uber Gelenktransplantation. Med Klin 4: 817
MacEwen W (1881) Observations concerning transplantation of bones: Illustrated by a case of interhuman osseous transplantations, whereby over two-thirds of the shaft of a humerus was restored. Proc Roy Soc London 32: 232 – 247
Mankin HJ, Friedlaender GE (1989) Bone and cartilage allografts: physiological and immunologi¬cal principles. In: Chandler HP, Penenberg BL (eds) Bone stock deficiency in total hip replacement. Thorofare, NJ: Slack, chapter 1
McCollum DE, Nunley JA, Harrelson JM (1980) Bone grafting in THR for acetabular protrusion. JBJS 72-A: 248 – 252
Oilier L (1867) Traite experimental et clinique de la regeneration des os et de la production artificielle du tissue osseux. Victor Masson et Fils: Paris
Ottolenghi CE (1972) Massive osteo and osteoarticular bone grafts. Technique and results of 62 cases. Clin Orthop 87: 156 – 164
Scales JT, Wright KWJ (1983) Major bone and joint replacement using custom implants. In: Chao EYs, Irin IC (eds) Tumor prosthesis for bone and joint reconstruction, the design and application. Stuttgart: Thieme, pp 149 – 168
Schreurs BW, Huiskes R, Slooff TJJH (1990) Proceedings 7th Meeting European Society of Biomechanics, Aarhus, DK, A14
Schreurs W, Huiskes R, Slooff TJJH, Buma P (1992) A method to estimate the initial stability of cemented and non-cemented hip stems fixated with a bone grafting technique. In: Older J (ed) Bone implant grafting. Berlin: Springer, chapter 18, pp 131 – 134
Schreurs BW, Buma P, Huiskes R, Slagter JLM, Slooff TJJH (1993) Transactions ORS, 452, San Francisco, USA
Schreurs BW, Buma P, Huiskes R, Slagter JLM, Slooff TJJH (1994) A technique for using im¬pacted trabecular allografts in revision surgery with cemented stems. Acta Orthop Scand 65: 267 – 275
Schreurs BW, Huiskes R, Slooff TJJH (1994) The initial stability of cemented and noncemented femoral stems fixated with a bone grafting technique. Clin Mater 16: 105 – 110
Selvik G (1989) Roentgen stereophotogrammetry. Acta Orthop Scand 60 [Suppl 232]
Selvik G (1974) A roentgenstereophotogrammatic method for the study of the kinematics of the skeletal system. Thesis, University of Lund, Lund, Sweden
Slooff TJ, Van Horn J, Lemes A, Fluiskes R (1984) Bone grafting for total hip replacement for acetabular protrusion. Acta Orthop Scand 55: 593 – 596
Slooff TJJH (1992) Acetabular augmentation in cemented arthroplasty: pre-operative assess¬ment and surgical technique. In: Older J (ed) Bone implant grafting. Berlin: Springer, chapter 8, pp 51 – 55
Stevenson S, Xiao Qing Li, Martin B (1991) The fate of cancellous and cortical bone after transplantation of fresh and frozen tissue-antigen-matched and mismatched osteochondral allografts in dogs. J Bone Joint Surg 73-A: 1143 – 1157
Urist MR (1953) The physiological basis of bone graft surgery, with special reference to the theory of induction. Clin Orthop 1: 207
Urist MR (1965) Bone: formation by auto-induction. Science 150: 893 – 899
Urist MR, De Lange RJ, Finerman GA (1983) Bone cell differentiation and growth factors. Science 220: 680
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer-Verlag/Wien
About this chapter
Cite this chapter
Slooff, T.J.J.H., Buma, P., Schimmel, J.W., Gardeniers, J., Huiskes, R. (1996). Impaction Grafting and Cement in Acetabular Revision Arthroplasty. In: Czitrom, A.A., Winkler, H. (eds) Orthopaedic Allograft Surgery. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6885-1_15
Download citation
DOI: https://doi.org/10.1007/978-3-7091-6885-1_15
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-7423-4
Online ISBN: 978-3-7091-6885-1
eBook Packages: Springer Book Archive