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Concepts on the prognostic significance of white matter changes

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Ageing and Dementia

Part of the book series: Journal of Neural Transmission. Supplementa ((NEURAL SUPPL,volume 53))

Summary

Magnetic resonance imaging white matter changes are a common observation in the elderly. The prognostic significance of such abnormalities is incompletely understood. Correlative studies which are reviewed here, suggested a predictive potential of white matter abnormalities for ischemic stroke, intracerebral hemorrhage, cognitive decline or even dementia. According to current review of literature the most compelling evidence for such a relationship exists for intellectual dysfunction. So far, there exist only preliminary data on the rate of WMH progression, but these demonstrate, at least some increase in number or extent within relatively short observational periods.

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Authors and Affiliations

  1. Department of Neurology, Karl Franzens University Graz, Auenbruggerplatz 22, A-8036, Graz, Austria

    P. Kapeller & R. Schmidt

Authors
  1. P. Kapeller
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  2. R. Schmidt
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Editor information

Editors and Affiliations

  1. Ludwig-Boltzmann-Institut für Klinische Neurobiologie, Wien, Österreich, Austria

    K. Jellinger (Prof. Dr.) (Prof. Dr.)

  2. Universitätsklinik für Neurologie, Graz, Österreich, Austria

    F. Fazekas (Prof. Dr.) (Prof. Dr.)

  3. Institut für Experimentelle Pharmakologie, Forschungsinitiative EBEWE, Graz, Österreich, Austria

    M. Windisch (Dr.) (Dr.)

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© 1998 Springer-Verlag Wien

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Kapeller, P., Schmidt, R. (1998). Concepts on the prognostic significance of white matter changes. In: Jellinger, K., Fazekas, F., Windisch, M. (eds) Ageing and Dementia. Journal of Neural Transmission. Supplementa, vol 53. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6467-9_6

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  • DOI: https://doi.org/10.1007/978-3-7091-6467-9_6

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83114-4

  • Online ISBN: 978-3-7091-6467-9

  • eBook Packages: Springer Book Archive

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