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Konzentrationsbestimmungen von Pharmaka im Serum. Pharmakokinetische und pharmakodynamische Parameter der Therapiekontrolle

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Konzentrationsmessungen von Pharmaka, Bedeutung für Klinik und Praxis

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Zusammenfassung

Eine fundamentale Prämisse in der Pharmakologie besagt, daß die pharmakologische Wirkung durch die Menge des Pharmakons am Wirkort bestimmt wird. Die Menge des Pharmakons am Wirkort ist eine Funktion der applizierten Dosis. Zwischen der Applikation des Arzneimittels und der Stärke seiner pharmakologischen Wirkung sind zahlreiche Vorgänge eingeschaltet, die enorme intra- und interindividuelle Unterschiede in der Dosis/Wirkungsbeziehung hervorrufen können.

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  1. Innere Abteilung, Schloßparkklinik Berlin, Deutschland

    H.-F. Vöhringer & G. A. Neuhaus

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  1. H.-F. Vöhringer
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  2. G. A. Neuhaus
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K. Hierholzer N. Rietbrock

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© 1980 Springer Fachmedien Wiesbaden

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Vöhringer, HF., Neuhaus, G.A. (1980). Konzentrationsbestimmungen von Pharmaka im Serum. Pharmakokinetische und pharmakodynamische Parameter der Therapiekontrolle. In: Hierholzer, K., Rietbrock, N. (eds) Konzentrationsmessungen von Pharmaka, Bedeutung für Klinik und Praxis. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-14065-8_2

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  • DOI: https://doi.org/10.1007/978-3-663-14065-8_2

  • Publisher Name: Vieweg+Teubner Verlag, Wiesbaden

  • Print ISBN: 978-3-528-07904-8

  • Online ISBN: 978-3-663-14065-8

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