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Für Logopäden relevante neurologische Funktionsstörungen

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Neurologie für Logopäden
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Zusammenfassung

In diesem Kapitel werden alle neurologischen Funktionsstörungen, deren Behandlung zu den logopädischen Aufgaben gehört, systematisch dargestellt: Sensibilitätsstörungen des Gesichts und/oder Mundes, Funktionsstörungen der mimischen Muskulatur, Funktionsstörungen der Kaumuskulatur und Zungenmuskulatur, Störungen des Schluckens, Sprechens und der Sprache sowie abschließend das apallische Syndrom und das Locked-in-Syndrom. Die Darstellung beginnt bei den funktionellen und anatomischen Grundlagen über die für die jeweiligen Krankheiten charakteristischen Symptome, ihre Ursachen sowie die wichtigsten Fakten zur medizinischen Diagnostik und Therapie. Am Ende jeden Abschnitts werden Hinweise zur die logopädischen Therapie gegeben.

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Literatur

  • Ackermann H et al (2018) Neurogene Sprechstörungen (Dysarthrien), S1-Leitlinie, 2018. In: Deutsche Gesellschaft für Neurologie (Hrsg) Leitlinien für Diagnostik und Therapie in der Neurologie. www.dgn.org/leitlinien. Zugegriffen am 15.07.2018

  • de Almeida JR, Al Khabori M, Guyatt GH, Witterick IJ, Lin VY, Nedzelski JM, Chen JM (2009) Combined corticosteroid and antiviral treatment for Bell palsy: a systematic review and meta-analysis. JAMA 302:985–993

    Article  PubMed  Google Scholar 

  • ANCDS (Academy of Neurologic Communication Disorders and Sciences) (2009) Technical Report 1, 09/20/02. www.ancds.org. Menüpunkt Practice Guidelines

  • Anis MM, Memon Z (2018) Injection medialization laryngoplasty improves dysphagia in patients with unilateral vocal fold immobility. World J Otorhinolaryngol Head Neck Surg 4:126–129

    Article  PubMed  PubMed Central  Google Scholar 

  • Attal N, Cruccu G, Baron R, Haanpää M, Hansson P, Jensen TS, Nurmikko T, European Federation of Neurological Societies (2010) EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur J Neurol 17:1113-e88

    Google Scholar 

  • Balardin JB, Miotto EC (2009) A review of constraint-induced therapy applied to aphasia rehabilitation in stroke patients. Dement Neuropsychol 3:275–282

    Article  PubMed  PubMed Central  Google Scholar 

  • Barritt AW, Smithard DG (2009) Role of cerebral cortex plasticity in the recovery of swallowing function following dysphagic stroke. Dysphagia 24:83–90

    Article  PubMed  Google Scholar 

  • Biniek R (1993) Akute Aphasien. Thieme, Stuttgart

    Google Scholar 

  • Breitenstein C, Kramer K, Meinzer M et al (2009) Intensives Sprachtraining bei Aphasie. Einfluss kognitiver Faktoren. Nervenarzt 80:149–150

    Article  CAS  PubMed  Google Scholar 

  • Bryant M (1991) Biofeedback in the treatment of a selected dysphagic patient. Dysphagia 6:140–144

    Article  CAS  PubMed  Google Scholar 

  • Carnaby G, Hankey GJ, Pizzi J (2006) Behavioural intervention for dysphagia in acute stroke: a randomised controlled trial. Lancet Neurol 5:31–37

    Article  PubMed  Google Scholar 

  • Carrau RL, Murry T (2000) Evaluation and management of adult dysphagia and aspiration. Curr Opin Otolaryngol Head Neck Surg 8:489–496

    Article  Google Scholar 

  • Casanova E, Lazzari RE, Lotta S, Mazzuchi A (2003) Locked-in syndrome: improvement in the prognosis after an early intensive multidisciplinary rehabilitation. Arch Phys Rehabil 84:862–867

    Article  Google Scholar 

  • Cherney LR, Patterson JP, Raymer A, Frymark T, Schooling T (2008) Evidence-based systematic review: effects of intensity of treatment and constraint-induced language therapy for individuals with stroke-induced aphasia. J Speech Lang Hear Res 51:1282–1299

    Article  PubMed  Google Scholar 

  • Chiang CF, Lin MT, Hsiao MY et al (2018) comparative efficacy of noninvasive neurostimulation therapies for acute and subacute poststroke dysphagia: a systematic review and network meta-analysis. Arch Phys Med Rehabil. pii: S0003-9993(18)31379-0

    Google Scholar 

  • Crary MA, Carnaby Mann GD, Groher ME et al (2004) Functional benefits of dysphagia therapy using adjunctive sEMG biofeedback. Dysphagia 19:160–164

    PubMed  Google Scholar 

  • Crinion J, Price CJ (2005) Right anterior superior temporal activation predicts auditory sentence comprehension following aphasic stroke. Brain 128:2858–2871

    Article  PubMed  Google Scholar 

  • De Renzi E, Vignolo LA (1962) The token test: a sensitive test to detect receptive disturbances in aphasics. Brain 85:665–678

    Article  Google Scholar 

  • Deane KHO, Whurr R, Playford ED et al (2006a) Speech and language therapy versus placebo or no intervention for dysarthria in Parkinson’s disease. The Cochrane Library, Oxford (Update Software)

    Google Scholar 

  • Deane KHO, Whurr R, Playford ED et al (2006b) Speech and language therapy for dysarthria in Parkinson’s disease: a comparison of techniques. The Cochrane Library, Oxford (Update Software)

    Google Scholar 

  • Dezfulian C, Shojania K, Collard HR et al (2005) Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med 118:11–18

    Article  PubMed  Google Scholar 

  • Dijkerman HC, Wood VA, Hewer RL (1996) Long term outcome after discharge from a stroke rehabilitation unit. JR Coll Physicians Lond 30:538–546

    CAS  Google Scholar 

  • Dressler D, Gelderblom M (2018) Dystonie. In: Diener HC, Gerloff C, Dieterich M (Hrsg) Therapie und verlauf neurologischer Erkrankungen. Kohlhammer, Stuttgart, S 1120–1130

    Google Scholar 

  • Dziewas R, Stellato R, van der Tweel I et al (2018) Pharyngeal electrical stimulation for early decannulation in tracheotomised patients with neurogenic dysphagia after stroke (PHAST-TRAC): a prospective, single-blinded, randomised trial. Lancet Neurol 17:849–859

    Article  PubMed  Google Scholar 

  • Eisenhardt SU (2017) Kommentar im Auftrag der Deutschen Gesellschaft für Plastische, Rekonstruktive und Ästhetische Chirurgie (DGPRÄC). https://www.dgn.org/leitlinien/3432-030-013-therapie-der-idiopathischen-fazialisparese-bell-s-palsy-2017. Zugegriffen am 31.03.2017

  • Engström M, Berg T, Stjernquist-Desatnik A, Axelsson S, Pitkäranta A, Hultcrantz M, Kanerva M, Hanner P, Jonsson L (2008) Prednisolone and valaciclovir in Bell’s palsy: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet Neurol 7:993–1000

    Article  PubMed  Google Scholar 

  • Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M (2015) Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 14:162–173

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Flöel A, Ackermann H (2018) Aphasie. In: Diener HC, Gerloff C, Dieterich M (Hrsg) Therapie und Verlauf neurologischer Erkrankungen. Kohlhammer, Stuttgart, S 261–269

    Google Scholar 

  • Fridriksson J (2010) Preservation and modulation of specific left hemisphere regions is vital for treated recovery from anomia in stroke. J Neurosci 30:1158–1164

    Article  CAS  Google Scholar 

  • Frost J, Robinson HF, Hibberd J (2018) A comparison of neuromuscular electrical stimulation and traditional therapy, versus traditional therapy in patients with longstanding dysphagia. Curr Opin Otolaryngol Head Neck Surg 26:167–173

    Article  PubMed  Google Scholar 

  • Fujiu M, Logemann JA (1996) Effect of a tongue-holding maneuver on posterior wall movement during deglutition. Am J Speech Lang Pathol 5:23–30

    Article  Google Scholar 

  • Goldenberg G, Spatt J (1994) Influence of size and site of cerebral lesions on spontaneous recovery of aphasia and on success of language therapy. Brain Lang 47:684–698

    Article  CAS  PubMed  Google Scholar 

  • Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, Ogar JM, Rohrer JD, Black S, Boeve BF, Manes F, Dronkers NF, Vandenberghe R, Rascovsky K, Patterson K, Miller BL, Knopman DS, Hodges JR, Mesulam MM, Grossman M (2011) Classification of primary progressive aphasia and its variants. Neurology 76:1006–1014

    Article  PubMed  PubMed Central  Google Scholar 

  • Gross G (2005) Zoster und Zosterschmerzen, Leitlinien der Dermatologischen Gesellschaft, Arbeitsgemeinschaft Dermatologische Infektiologie. http://www.awmf-leitlinien.de

  • Hirst LJ, Sama A, Carding PM et al (1998) Is a ‚safe swallow‘ really safe? Int J Lang Commun Disord 33(Suppl):279–280

    Article  PubMed  Google Scholar 

  • Holland AL, Fromm DS, Deruyter F et al (1996) Treatment efficacy: aphasia. J Speech Hear Res 39:227–236

    Article  Google Scholar 

  • Huber W, Poeck K, Weniger D, Willmes K (1983) Aachener Aphasie-Test (AAT). Hogrefe, Göttingen

    Google Scholar 

  • Huckabee ML, Butler SG, Barclay M et al (2005) Submental surface electromyographic measurement and pharyngeal pressures during normal and effortful swallowing. Arch Phys Med Rehabil 86:2144–2149

    Article  PubMed  Google Scholar 

  • Kahrilas PJ, Logemann JA, Krugler C et al (1991) Volitional augmentation of upper esophageal sphincter opening during swallowing. Am J Phys 260:G450–G456

    CAS  Google Scholar 

  • Kanai A, Suzuki A, Kobayashi M, Hoka S (2006) Intranasal lidocaine 8 % spray for second-division trigeminal neuralgia. Br J Anaesth 97:559–563

    Article  CAS  PubMed  Google Scholar 

  • Kanpolat Y, Savas A, Bekar A, Berk C (2001) Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1,600 patients. Neurosurgery 48:524–532; discussion 532–534

    Google Scholar 

  • Karbe H, Herholz K, Halber M, Heiss WD (1998) Collateral inhibition of transcallosal activity facilitates functional brain asymmetry. J Cereb Blood Flow Metab 18:1157–1161

    Article  CAS  PubMed  Google Scholar 

  • Kastrup O, Hermann DM, Diener HC (2017) Nebenwirkungen medikamentöser Therapie in der Neurologie. In: Diener HC, Gerloff C, Dieterich M (Hrsg) Therapie und Verlauf neurologischer Erkrankungen, 7., erw. u. überarb. Aufl. Kohlhammer, Stuttgart

    Google Scholar 

  • Kelly JH (2000) Management of upper esophageal sphincter disorders: indications and complications of myotomy. Am J Med 108(Suppl 4a):43S–46S

    Article  PubMed  Google Scholar 

  • Kelly H, Brady MC, Enderby P (2010) Speech and language therapy for aphasia following stroke. Cochrane Database Syst Rev (5):CD000425

    Google Scholar 

  • Kondziolka D, Lunsford LD, Bissonette DJ (1994) Long-term results after glycerol rhizotomy for multiple sclerosis-related trigeminal neuralgia. Can J Neurol Sci 21:137–140

    Article  CAS  PubMed  Google Scholar 

  • Kos MP, David EF, Klinkenberg-Knol EC et al (2010) Long-term results of external upper esophageal sphincter myotomy for oropharyngeal Dysphagia. Dysphagia 25:169–176

    Article  PubMed  Google Scholar 

  • Kuhlemeier KV, Palmer JB, Rosenberg D (2001) Effect of liquid bolus consistency and delivery method on aspiration and pharyngeal retention in dysphagia patients. Dysphagia 16:119–122

    Article  CAS  PubMed  Google Scholar 

  • Lambon Ralph MA, Snell C, Fillingham JK et al (2010) Predicting the outcome of anomia therapy for people with aphasia post CVA: both language and cognitive status are key predictors. Neuropsychol Rehabil 20:289–305

    Article  PubMed  Google Scholar 

  • Langmore SE, Terpenning MS, Schork A et al (1998) Predictors of aspiration pneumonia: how important is dysphagia? Dysphagia 13:69–81

    Article  CAS  PubMed  Google Scholar 

  • Laska AC, Hellblom A, Murray V et al (2001) Aphasia in acute stroke and relation to outcome. J Intern Med 249:413–422

    Article  CAS  PubMed  Google Scholar 

  • Lauer N (2010) Sprechapraxie im Kindes- und Erwachsenenalter, 2. Aufl. Thieme, Stuttgart

    Google Scholar 

  • Lazar RM, Antoniello D (2008) Variability in recovery from aphasia. Curr Neurol Neurosci Rep 8:497–502

    Article  PubMed  Google Scholar 

  • Lazar RM, Speizer AE, Festa JR et al (2008) Variability in language recovery after first-time stroke. J Neurol Neurosurg Psychiatry 79:530–534

    Article  CAS  PubMed  Google Scholar 

  • Lazar RM, Minzer B, Antoniello D et al (2010) Improvement in aphasia scores after stroke is well predicted by initial severity. Stroke 41:1485–1488

    Article  PubMed  PubMed Central  Google Scholar 

  • Lazarus C, Logemann JA, Song CW et al (2002) Effects of voluntary maneuvers on tongue base function for swallowing. Folia Phoniatr Logop 54:171–176

    Article  PubMed  Google Scholar 

  • Lee EI, Hurvitz KA, Evans GR, Wirth GA (2008) Cross-facial nerve graft: past and present. J Plast Reconstr Aesthet Surg 61:250–256

    Article  PubMed  Google Scholar 

  • Leger A, Demonet JF, Aithamon B et al (2002) Neural substrates of spoken language rehabilitation in an aphasic patient: an fMRI study. NeuroImage 17:174–183

    Article  CAS  PubMed  Google Scholar 

  • Logemann JA, Kahrilas PJ, Kobara M et al (1989) The benefit of head rotation on pharyngoesophageal dysphagia. Arch Phys Med Rehabil 70:767–771

    CAS  PubMed  Google Scholar 

  • Logemann JA, Gensler G, Robbins J et al (2008) A randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson’s disease. J Speech Lang Hear Res 51:173–183

    Article  PubMed  Google Scholar 

  • Lule D, Zickler C, Hacker S et al (2009) Life can be worth living in locked-in syndrome. Prog Brain Res 177:339–351

    Article  CAS  PubMed  Google Scholar 

  • Meinzer M, Breitenstein C (2008) Functional imaging studies of treatment-induced recovery in aphasia. Aphasiology 22:1251–1268

    Article  Google Scholar 

  • Meinzer M, Djundja D, Barthel G, Elbert T, Rockstroh B (2005) Long-term stability of improved language functions in chronic aphasia after constraint-induced aphasia therapy. Stroke 36:1462–1466

    Article  PubMed  Google Scholar 

  • Meinzer M, Mohammadi S, Kugel H et al (2010) Integrity of the hippocampus and surrounding white matter is correlated with language training success in aphasia. Neuroimage 53:283–290

    Article  PubMed  Google Scholar 

  • Mepani R, Antonik S, Massey B et al (2009) Augmentation of deglutitive thyrohyoid muscle shortening by the shaker exercise. Dysphagia 24:26–31

    Article  PubMed  Google Scholar 

  • Miller RG, Rosenberg JA, Gelinas DF et al (1999) Practice parameter: the care of the patient with amyotrophic lateral sclerosis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology: ALS Practice Parameters Task Force. Neurology 52:1311–1323

    Article  CAS  PubMed  Google Scholar 

  • Nakagawa T, Wada H, Sekizawa K et al (1999) Amantadine and pneumonia. Lancet 353:1157

    Article  CAS  PubMed  Google Scholar 

  • Ohmae Y, Logemann JA, Hanson DG et al (1996) Effects of two breath-holding maneuvers on oropharyngeal swallow. Ann Otol Rhinol Laryngol 105:123–131

    Article  CAS  PubMed  Google Scholar 

  • Patel MA, Eytan DF, Bishop J, Califano JA (2017) Favorable Swallowing Outcomes following Vagus Nerve Sacrifice for Vagal Schwannoma resection. Otolaryngol Head Neck Surg 156:329–333

    Article  PubMed  Google Scholar 

  • Pedersen PM, Jorgensen HS, Nakayama H et al (1995) Aphasia in acute stroke: incidence, determinants, and recovery. Ann Neurol 38:659–666

    Article  CAS  PubMed  Google Scholar 

  • Power ML, Hamdy S, Singh S et al (2007) Deglutitive laryngeal closure in stroke patients. J Neurol Neurosurg Psychiatry 78:141–156

    Article  CAS  PubMed  Google Scholar 

  • Prosiegel M (2012) Neurogene Dysphagien. Rehabilitation lt. Leitlinien für Diagnostik und Therapie in der Neurologie, 5. Aufl. Heruntergeladen 17. Sept 2018

    Google Scholar 

  • Pulvermüller F, Neininger B, Elbert T et al (2001) Constraint-induced therapy of chronic aphasia after stroke. Stroke 32:1621–1626

    Article  PubMed  Google Scholar 

  • Ramig LO, Fox C, Sapir S (2004) Parkinson’s disease: speech and voice disorders and their treatment with the Lee Silverman Voice Treatment. Semin Speech Lang 25:169–180

    Article  PubMed  Google Scholar 

  • Rauer S, Kastenbauer S et al (2018) Neuroborreliose, S3-Leitlinie. In: Deutsche Gesellschaft für Neurologie (Hrsg) Leitlinien für Diagnostik und Therapie in der Neurologie. www.dgn.org/leitlinien. Zugegriffen am 10.09.2018

  • Regan J, Walshe M, Tobin WO (2010) Immediate effects of thermal-tactile stimulation on timing of swallow in idiopathic Parkinson’s disease. Dysphagia 25:207–215

    Article  PubMed  Google Scholar 

  • Richter M, Miltner WH, Straube T (2008) Association between therapy outcome and right-hemisperic activation in chronic aphasia. Brain 131:1391–1401

    Article  PubMed  Google Scholar 

  • Robbins J, Kays SA, Gangnon RE et al (2007) The effects of lingual exercise in stroke patients with dysphagia. Arch Phys Med Rehabil 88:150–158

    Article  PubMed  Google Scholar 

  • Robey RR (1998) A meta-analysis of clinical outcomes in the treatment of aphasia. J Speech Lang Hear Res 41:172–187

    Article  CAS  PubMed  Google Scholar 

  • Rosenbek JC, Robbins JA, Roecker EB et al (1996) A penetration-aspiration scale. Dysphagia 11:93–98

    Article  CAS  PubMed  Google Scholar 

  • Salinas RA, Alvarez G, Daly F, Ferreira J (2010) Corticosteroids for Bell’s palsy (idiopathic facial paralysis). Cochrane Database Syst Rev 2010 17(3):CD001942

    Google Scholar 

  • Saur D, Lange R, Baumgaertner A, Schraknepper V, Willmes K, Rijntjes M, Weiller C (2006) Dynamics of language reorganization after stroke. Brain 129:1371–1384

    Article  PubMed  Google Scholar 

  • Sciortino K, Liss JM, Case JL et al (2003) Effects of mechanical, cold, gustatory, and combined stimulation to the human anterior faucial pillars. Dysphagia 18:16–26

    Article  PubMed  Google Scholar 

  • Shaker R, Easterling C, Kern M et al (2002) Rehabilitation of swallowing by exercise in tube-fed patients with pharyngeal dysphagia secondary to abnormal UES opening. Gastroenterology 122:1314–1321

    Article  PubMed  Google Scholar 

  • Shanahan TK, Logemann JA, Rademaker et al (1993) Chin-down posture effect on aspiration in dysphagic stroke patients. Arch Phys Med Rehabil 74:736–739

    Article  CAS  PubMed  Google Scholar 

  • Sharkawi AE, Ramig L, Logemann JA et al (2002) Swallowing and voice effects of Lee Silverman Voice Treatment (LSVT®): a pilot study. J Neurol Neurosurg Psychiatry 72:31–36

    Article  PubMed  PubMed Central  Google Scholar 

  • Spillane JD (1975) An Atlas of clinical neurology, 2. Aufl. Oxford University Press, London

    Google Scholar 

  • Steele CM, Huckabee ML (2007) The influence of orolingual pressure on the timing of pharyngeal pressure events. Dysphagia 22:30–36

    Article  PubMed  Google Scholar 

  • Sullivan FM, Swan IR, Donnan PT, Morrison JM, Smith BH, McKinstry B, Davenport RJ, Vale LD, Clarkson JE, Hammersley V, Hayavi S, McAteer A, Stewart K, Daly F (2007) Early treatment with prednisolone or acyclovir in Bell’s palsy. N Engl J Med 357:1598–1607

    Article  CAS  PubMed  Google Scholar 

  • Suntrup-Krueger S, Ringmaier C, Muhle P (2018) Randomized trial of transcranial direct current stimulation for poststroke dysphagia. Ann Neurol 83:328–340

    Article  PubMed  Google Scholar 

  • Trapl M, Enderle P, Nowotny M et al (2007) Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen. Stroke 38:2948–2952

    Article  PubMed  Google Scholar 

  • Tsukamoto Y (2000) CT study of closure of the hemipharynx with head rotation in a case of lateral medullary syndrome. Dysphagia 15:17–18

    Article  CAS  PubMed  Google Scholar 

  • Volkert D et al (2006) ESPEN-Leitlinien Enterale Ernährung: Geriatrie. Clin Nutr 25:330–360

    Article  CAS  PubMed  Google Scholar 

  • Weber K, Pfister HW (1994) Clinical management of Lyme borreliosis. Lancet 343:1017–1020

    Article  CAS  PubMed  Google Scholar 

  • Willmes K, Poeck K (1984) Ergebnisse einer multizentrischen Untersuchung über die Spontanprognose von Aphasien vaskulärer Ätiologie. Nervenarzt 55:62–71

    CAS  PubMed  Google Scholar 

  • Winhuisen L, Thiel A, Schumacher B, Winhuisen L, Thiel A, Schumacher B (2005) Role of the contralateral inferior frontal gyrus in recovery of language function in poststroke aphasia: a combined repetitive transcranial magnetic stimulation and positron emission tomography study. Stroke 36:1759–1763

    Article  PubMed  Google Scholar 

  • Yamaya M, Yanai M, Ohrui T et al (2001) Interventions to prevent pneumonia among older adults. J Am Geriatr Soc 49:85–90

    Article  CAS  PubMed  Google Scholar 

  • Yorkston KM, Spencer KA, Duffy JR (2003) Behavioral management of respiratory/phonatory dysfunction from dysarthria: a systematic review of the evidence. J Med Speech-Lang Pathol 11:xviii–xxxviii

    Google Scholar 

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Winter, R., Bischoff, B. (2019). Für Logopäden relevante neurologische Funktionsstörungen. In: Neurologie für Logopäden. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58310-4_1

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