Zusammenfassung
Dermatologische Erkrankungen des Anorektums gehören mit zu den häufigsten Beschwerdebildern, mit denen der Proktologe, insbesondere in der Praxis, konfrontiert wird. Häufig ist Juckreiz das Hauptsymptom, das Analekzeme unterschiedlichster Genese auslösen können. Hier ist die Kenntnis der verschiedenen Differenzialdiagnosen entscheidend für die erfolgreiche Therapie. Es muss das Ekzem von Dermatosen und den diversen Infektionen abgegrenzt werden, wobei durch Geschlechtsverkehr übertragene Erkrankungen eine nicht unwesentliche Rolle spielen, wie Herpes-Infektionen oder auch die von humanen Papillomaviren induzierten Erkrankungen wie Condylomata acuminata. Die meisten dermatologischen Erkrankungen des Anorektums sind einer konservativen topischen oder auch systemischen Therapie zugänglich. Ausnahmen bilden die intraepithelialen Neoplasien, Malignome und jene Krankheiten, die unter dem Oberbegriff perianale/perineale Abszesse subsumiert werden können, wie die Akne inversa oder der Pilonidalsinus.
Das Kapitel wurde von G. Weyandt verfasst, mit Ausnahme des Abschnitts 12.8 (G. Weyandt, B. Bauer).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
Anand P (2003) Capsaicin and menthol in the treatment of itch and pain: recently cloned receptors provide the key. GUT 52: 1233–1235
Arican O, Guneri F, Bilgic K, Karaoglu A (2004) Topical imiquimod 5 % cream in external anogenital warts: A randomized, double-blind, placebo-controlled study. J Dermatol 31: 627–631
Atia WA, Ratnatunga GS, Greenfield C, et al. (1982) Aseptic meningitis and herpes simplex proctitis. Br J Vener Dis 58: 52–53
Attanoos RL, Appleton MAC, Douglas-Jones AG (1995) The pathogenesis of hidradenitis suppurativa: a closer look at apocrine and apoeccrine glands. Br J Dermatol 133: 254–258
AWMF online, Ständer S, Darsow U, Mettang T, et al. (Hrsg) Leitlinie der Deutschen Dermatologischen Gesellschaft chronischer Pruritus. www.awmf.org/leitlinien/detail/ll/013–048.html
Bechara FG, Hessam S (2016) Hidradenitis suppurativa. MMW 158: 52–53
Bechara FG, Sand M, Skrygan M, Kreuter A, Altmeyer P, Gambichler T (2012) Acne inversa: evaluating antimicrobial peptides and proteins. Ann Dermatol 24: 393–397
Beifuss B, Bezold G, Gottlöber P, et al. (2011) Direct detection of five common dermatophyte species in clinical samples using a rapid and sensitive 24-h PCR-ELISA technique open to protocol transfer. Mycoses 54: 137–145
Bettoli V, Naldi L, Cazzaniga S, et al. (2015) Overweight, diabetes and disease duration influence clinical severity in Hidradenitis Suppurativa – Acne Inversa. Evidence from the national Italian Registry. Brit J Dermatol 174: 195–197
Blecher T, Korting HC (1995) Tolerance to different toilet paper preparations: toxicological and allergological aspects. Dermatology 191: 299–304
Boer J, Weltevreden EF (1996) Hidradenitis suppurativa or acne inversa. A clinicopathological study of early lesions. Br J Dermatol 135: 721–725
Bratzke B, Orfanos CE, Stavermann T, et al. (1991) Chronisch erosiver therapieresistenter perianaler Herpes (Typ II) mit Herpes Proctitis bei einem AIDS-Kranken. Hautarzt 42: 96–100
Brühl W, Schmauz R (1997/8) Analhygiene bei perianalen Hauterkrankungen. Verträglichkeit von Wasser, feuchtem und trockenem Toilettenpapier. Zentralbl Hyg Umweltmedizin 200: 562–570
Brunsting HA (1939) Hidradenitis suppurativa: abscess of the apocrine sweat glands. Arch Derm Syphil 39: 108–120
Christian CW, Singer ML, Crawford JE, et al. (1997) Perianal herpes zoster presenting as suspected child abuse. Pediatrics 88: 608–610
Cohen R, Roth FJ, Delgado E, et al. (1969) Fungal flora of the normal human small and large intestine. N Engl J Med 280: 638–641
Cohen BA, Honig P, Androphy E (1990) Anogenital warts in children: clinical and virologic evaluation for sexual abuse. Arch Dermatol 126: 1575–1580
Daniel GL, Longo WE, Vernava AM (1994) Pruritus ani: Causes and concerns. Dis Colon Rectum 37: 670–674
Darragh TM, Colgan TJ, Thomas Cox J, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC (2013) The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Int J Gynecol Pathol 32: 76–115. doi: 10.1097/PGP.0b013e31826916c7
Darsow U, Vieluf D, Ring J (1995) Atopy patch test with different vehicles and allergen concentrations – an approach to standardisation. J Allergy Clin Immunol 95: 677–684
Dasan S, Neill SM, Donaldson DR, et al. (1999) Treatment of persistent pruritus ani in a combined colorectal and dermatological clinic. Br J Surg 86: 1337–1340
DeGroot AC, Baar TJM, Terpstra H, et al. (1991) Contact allergy to moist toilet paper. Contact Dermatitis 24: 135–136
Diepgen TL, Fartasch M, Hornstein OP (1991) Kriterien zur Beurteilung der atopischen Hautdiathese. Dermatosen 39: 79–83
Dinh H, Purcell SM, Chung C, Zaenglein AL (2016) Pediatric Lichen Sclerosus: A Review of the Literature and Management Recommendations. J Clin Aesthet Dermatol 9: 49–54
Dodi G, Prione E, Bettin A, et al. (1985) The mycotic flora in proctological patients with an without pruritus ani. Br J Surg 72: 967–969
Dogan A, Hilal Z, Krentel H, Cetin C, Hefler LA, Grimm C, Tempfer CB (2017) Paget’s Disease of the Vulva Treated with Imiquimod: Case Report and Systematic Review of the Literature. Gynecol Obstet Invest 82: 1–7
Edwards L, Ferenczy A, Eron L, Baker D, Owens ML, Fox TL, Hougham AJ, Schmitt KA (1998) Self-administered topical 5 % imiquimod cream for external anogenital warts. HPV Study Group. Human PapillomaVirus. Arch Dermatol 134: 25–30
Egeberg A, Gislason GH, Hansen PR (2016) Risk of Major Adverse Cardiovascular Events and All-Cause Mortality in Patients With Hidradenitis Suppurativa. JAMA Dermatol 152: 429–434
Egeberg A, Jemec GB, Kimball AB, et al. (2017) Prevalence and risk of inflammatory bowel disease in patients with hidradenitis suppurativa. J Invest Dermatol 137: 1060–1064
Emelianov VU, Bechara FG, Glaser R, et al. (2012) Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversa. Brit J Dermatol 166: 1023–1034
Engel JP, Englund JA, Fletcher CV, et al. (1990) Treatment of resistant herpes simplex virus with continous infusion acyclovir. JAMA 263: 1662–1664
Esser S, Kreuter A, Oette M, Gingelmaier A, Mosthaf F, Sautter-Bihl ML, Jongen J, Brockmeyer NH, Eldering G, Swoboda J, Postel N, Degen O, Schalk H, Jessen A, Knechten H, Thoden J, Stellbrink HJ, Schafberger A, Wieland UJ (2015) German-Austrian guidelines on anal dysplasia and anal cancer in HIV-positive individuals: prevention, diagnosis, and treatment. JDDG 13: 1302–1319. doi: 10.1111/ddg.12726
Fashner J, Bell AL (2011) Herpes zoster and postherpetic neuralgia: prevention and management. Am Fam Physician 83: 1432–1437
Gahlen W, Grussendorf EI, Wienert V (1976) Histologischer Beitrag zum Krankheitsbild der sogenannten Pyodermia fistulans sinifica als Ausdruck einer schweren Akne (= Akne conglobata et sinifica). Z Hautkr 51: 621–626
Gesierich A, Hamm H, Bröcker EB, Weyandt GH (2008) Mehrschichtige Argon Plasma Koagulation und Imiquimod Creme: eine wenig invasive, aber ausreichend radikale Kombinationstherapie bei ausgedehnter bowenoider Papulose. Geburtshilfe Frauenheilkd 68: 274–278
Goldblum JR, Hart WR (1998) Perianal Paget’s disease: a histological and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma. Am J Surg Pathol 22: 170–179
Goldstein AT, Marinoff SC, Christopher K, Srodon M (2005) Prevalence of vulvar lichen sclerosus in a general gynecology practice. J Reprod Med 50: 477–480
Groos G (2009) Differential diagnosis of condylomata acuminata. Indication for biopsie. Hautarzt 60: 465–471
Gross G, Becker N, Brockmeyer NH, et al. (2013) S3-Leitlinie zur Impfprävention HPV-assoziierter Neoplasien. AWMF-Register-Nr.: 082/002
Guet-Revillet H, Coignard-Biehler H, Jais JP, et al. (2014) Bacterial pathogens associated with hidradenitis suppurativa, France. Emerg Infect Dis 20: 1990–1998
Gupta R, Warren T, Wald A (2007) Lancet 370: 2127–2137
Happle R, Konig A (2011) Smoker’s boils. Dermatology 222: 282–284
Harrison BJ, Mudge M, Hughes LE (1987) Recurrence after surgical treatment of hidradenitis suppurativa. Br Med J 294: 487–489
Havlickova B, Weyandt GH (2014) Therapeutic management of anal eczema: an evidence-based review. Int J Clin Pract 68: 1388–1399. doi:10.1111/ijcp.12457
Helle S (1973) Pruritus und Eczema ani bei Candidiasis. Phlebol Proktol 2: 41–43
Heller M, Dix RD, Baringer JR, et al. (1982) Herpetic proctitis and meningitis: recovery of two strains of herpes simplex virus type 1 from cerebrospinal fluid. J Infect Dis 146: 584–588
Herrera S, Rodriguez Pichardo A, Garcio Bravo B, et al. (1990) Verruces ano-genitales chez les enfants. Ann Dermatol Venereol 117: 523–526
Hessam S, Sand M, Gambichler T, Bechara FG (2015) Correlation of inflammatory serum markers with disease severity in patients with hidradenitis suppurativa (HS). J Am Acad Dermatol 73: 998–1005
Ingram JR (2016) The Genetics of Hidradenitis Suppurativa. Dermatol Clin 34: 23–28
Jellinek EH, Selby Tulloch W (1976) Herpes zoster with dysfunction of bladder and anus. Lancet 2: 1219–1222
Jensen SL, Sjölin KE, Shokouh Amiri MH, et al. (1988) Paget’s disease of the anal margin. Br J Surg 75: 1089–1092
Jones RW, Scurry J, Neill S, MacLean AB (2008) Guidelines for the follow-up of women with vulvar lichen sclerosus in specialist clinics. Am J Obstet Gynecol 198: 496e1–3
Kelly G, Hughes R, Mc Garry T, et al. (2015) Dysregulated cytokine expression in lesional and non-lesional skin in Hidradenitis suppurativa. Brit J Dermatol 173: 1431–1439
Kimball AB, Okun MM, Williams DA, et al. (2016) Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa. New Engl J Med 375: 422–434
Kizer WS, Prarie T, Morey AF (2003) Balanitis xerotica obliterans: epidemiologic distribution in an equal access health care system. South Med J 96: 9–11
Konig A, Lehmann C, Rompel R, Happle R (1999) Cigarette smoking as a triggering factor of hidradenitis suppurativa. Dermatology 198: 261–264
Konstantinova AM, Shelekhova KV, Stewart CJ, Spagnolo DV, Kutzner H, Kacerovska D, Plaza JA, Suster S, Bouda J, Pavlovsky M, Kyrpychova L, Michal M, Guenova E, Kazakov DV (2016) Depth and Patterns of Adnexal Involvement in Primary Extramammary (Anogenital) Paget Disease. Am J Dermatopathol 38: 802–808
Koutsky LA, Galloway DA, Holmes KK (1988) Epidemiology of genital human papillomavirus infection. Epidemiol Rev 10: 122–133
Krauspe C, Stelzner F (1962) Die Pyodermia fistulans sinifica. Chirurg 33: 534–538
Kreuter A, Siorokos C, Oellig F, Silling S, Pfister H, Wieland U (2016) High-grade Dysplasia in Anogenital Warts of HIV-Positive Men. JAMA Dermatol 152: 1225–1230. doi:10.1001/jamadermatol.2016.2503
Kyriazanos ID, Stamos NP, Miliadis L, Noussis G, Stoidis CN (2011) Extra- mammary Paget’s disease of the perianal region: a review of the literature emphasizing the operative management technique. Surg Oncol 20: e61–e71
Lacey CJ, Goodall RL, Tennvall GR, Maw R, Kinghorn GR, Fisk PG, Barton S, Byren I; Perstop Pharma Genital Warts Clinical Trial Group (2003) Randomised controlled trial and economic evaluation of podophyllotoxin solution, podophyllotoxin cream, and podophyllin in the treatment of genital warts. Sex Transm Infect 79: 270–275
Lane JE (1933) Hidradenitis axillaris of Verneuil. Arch Derm Syph 28: 609–614
Lebwohl M, Freeman AK, Chapman MS, et al. (2004) Tacrolimus ointment is effective for facial and intertriginous psoriasis. J Am Acad Dermatol 51: 723–730
Lentner A, Wienert V (1996) Plane Kondylome. Haut- und Geschlechtskr 71: 630–632
Lima AL, Karl I, Giner T, et al. (2016) Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa. Brit J Dermatol 174: 514–521
Mahal H (1972) Mykologische Untersuchungen bei Analekzem von Erwachsenen und Kindern. Hautarzt 23: 228–229
Mahalingam R, Wellish MC, Dueland AN, et al. (1992) Localization of herpes simplex virus and varicella-zoster-virus DNA in human ganglia. Ann Neurol 31: 444–448
Mallick-Searle T, Snodgrass B, Brant JM (2016) Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology. J Multidis Healthcare9: 447–454. doi:10.2147/JMDH.S106340
Manhart LE, Koutsky LA (2002) Do condomes prevent genital HPV infection external genital warts, or cervical neoplasia? A Meta-analysis. Sex Transm Dis 29: 725–735
Masson JK (1969) Surgical treatment for hidradenitis suppurativa. Surg Clin North Am 49: 1043–1052
Matusiak L, Szczech J, Bieniek A, Nowicka-Suszko D, Szepietowski JC (2017) Increased interleukin (IL)-17 serum levels in patients with hidradenitis suppurativa: Implications for treatment with anti-IL-17 agents. J Am Acad Dermatol 76: 670–675
Menuck LS, Brahme F, Amberg J, et al. (1976) Colonic changes of herpes zoster. Am J Roentgenol 127: 273–276
Minviella L, Hernandez VL (1969) The use of intralesional triamcinolone hexacetonide in treatment of idiopathic pruritus ani. Dis Colon Rectum 12: 340–343
Moore RA, Edwards JE, Hopwood J, et al. (2001) Imiquimod for the treatment of genital warts: a quantitative systematic review. BMC Infect Dis 1: 3
Morgan WT, Harding KG, Hughes LE (1983) A comparison of skin grafting and healing by granulations following axillary excision for hidradenitis suppurativa. Ann Roy Coll Surg 65: 235–236
Neill SM, Lewis FM, Tatnall FM, Cox NH (2010) British Association of Dermatologists’ guidelines for the management of lichen sclerosus 2010. Br J Dermatol 163: 672–682
Nikolakis G, Liakou AI, Bonovas S, et al. (2017) Bacterial Colonization in Hidradenitis Suppurativa/Acne Inversa: A Cross-sectional Study of 50 Patients and Review of the Literature. Acta dermato-venereologica 97 (in press)
Oates JK, Greenhouse PR (1978) Retention of urine in anogenital herpetic infection. Lancet 8086: 691–692
Obalek S, Misiewicz J, Jablonska S, et al. (1993) Childhood condylomata acuminate: association with genital and cutaneous human papillomaviruses. Pediatr Dermatol 10: 101–106
O’Connor WJ, et al. (2003) Comparison of mohs micrographic surgery and wide excision for extramammary Paget’s disease. Dermatol Surg 29: 723–727
Ohara K, Fujisawa Y, Yoshino K, Kiyohara Y, Kadono T, Murata Y, Uhara H, Hatta N, Uchi H, Matsushita S, Takenouchi T, Hayashi T, Yoshimura K, Fujimoto M (2016) A proposal for a TNM staging system for extramammary Paget disease: Retrospective analysis of 301 patients with invasive primary tumors.J Dermatol Sci 83: 234–239
Paget J (1874) One disease of the mammary areola proceeding cancer of the mammary gland. St Bart Hosp Rep 1874: 1087–1091
Paradisi M, Cianchini G, Angelo C, et al. (1994) Perianal streptococcal dermatitis. Two familial cases. Cutis 54: 341–342
Patel M, Cohen JM, Wright NA, Merola JF, Qureshi AA, Vleugels RA (2015) Epidemiology of concomitant psoriasis and hidradenitis suppurativa (HS): experience of a tertiary medical center. J Am Acad Dermatol 73: 701–702
Petersen CS, Weismann K (1995) Quercetin and kaempherol: an argument against the use of podophyllin? Genitourin Med 71: 92–93
Pharmazeutisches Laboratorium des DAC/NRF (Hrsg) (2017) Standardisierte Rezepturen. Formelsammlung für Ärzte, 9. Aufl. Govi, Eschborn
Pierie JP, Choudry U, Muzikansky A, Finkelstein DM, Ott MJ (2003) Prognosis and management of extramammary Paget’s disease and the association with secondary malignancies. J Am Coll Surg 196: 45–50
Pirone E, Infantino A, Masin E, et al. (1992) Can proctological procedures resolve perianal pruritus and mycosis? A prospective study of 23 cases. Int J Colorectal Dis 7: 18–20
Plewig G, Steger M (1989) Acne inversa. In: Marks R, Plewig G (eds) Acne and related disorders. Martin Dunitz, London, pp 345–347
Reichardt F, Vogt HJ (1975) Anorektaler Symptomenkomplex bei Zoster sacralis. Hautarzt 26: 383–384
Revuz JE, Canoui-Poitrine F, Wolkenstein P, et al. (2008) Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol 59: 596–601
Ring HC, Bay L, Nilsson M, et al. (2017) Bacterial Biofilm in Chronic Lesions of Hidradenitis Suppurativa. Brit J Dermatol 176: 996–1000
RKI (2014) Mitteilung der Ständigen Impfkommission am Robert Koch-Institut(RKI). Empfehlungen der Ständigen Impfkommission (STIKO) am Robert Koch-Institut/Stand: August 2014. Epid Bull 34: 315
Roberts JR, Siekas LL, Kaz AM (2017) Anal intraepithelial neoplasia: A review of diagnosis and management.World J Gastrointest Oncol 9: 50–61. doi: 10.4251/wjgo.v9.i2.50
Römer A, Greiner A, Enk A, Hartschuh W (2008) Herpes simplex vegetans: eine atypische genitale Herpesinfektion mit ausgeprägter Plasmazellinfiltration bei chronischer lymphatischer B-Zell-Leukämie. J Dtsch Dermatol Ges 6: 865–867
Sauerbrei A (2016) Herpes Genitalis: Diagnosis, Treatment and Prevention. Geburtshilfe Frauenheilkd 76: 1310–1317
Sauerbrei A, Sommer M, Wutzler P (1999) Virologische Diagnostik bei Herpes zoster. Hautarzt 50: 873–878
Sauerbrei A, Bohn-Wippert K, Kaspar M. et al. (2016) Database on natural polymorphisms and resistance-related non-synonymous mutations in thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and 2. J Antimicrob Chemother 71: 6–16
Sauerbrei A, Schmitt S, Scheper T, Brandstädt A , Saschenbrecker S, Motz M, et al. (2011) Seroprevalence of herpes simplex virus type 1 and type 2 in Thuringia, Germany, 1999 to 2006. Eur Surv 16: 1–7
Schiefferdecker B (1922) Die Hautdrüsen der Menschen und der Säugetiere, ihre histologische und rassenanatomische Bedeutung sowie die muscularis sexualis. Schweizerbart‘sche Verlagsbuchhandlung, Stuttgart
Schlapbach C, Hanni T, Yawalkar N, Hunger RE (2011) Expression of the IL-23/Th17 pathway in lesions of hidradenitis suppurativa. J Am Acad Dermatol 65: 790–798
Schneider KW (1976) Zur Behandlung von Hefen bei perianaler Dermatitis. Phlebol Proktol 5: 160–164
Schneider-Burrus S, Witte-Haendel E, Christou D, Rigoni B, Sabat R, Diederichs G (2012) High Prevalence of Back Pain and Axial Spondyloarthropathy in Patients with Hidradenitis Suppurativa. Dermatology 232: 606–612
Schofer H, Van Ophoven A, Henke U, Lenz T, Eul A (2006) Randomized, comparative trial on the sustained efficacy of topical imiquimod 5 % cream versus conventional ablative methods in external anogenital warts. Eur J Dermatol 16: 642–648
Shahi V, Alikhan A, Vazquez BG, Weaver AL, Davis MD (2014) Prevalence of hidradenitis suppurativa: a population-based study in Olmsted County, Minnesota. Dermatology 229: 154–158
Skinner PP, Ogunbiyi OA, Scholefield JH, Start RD, Smith JH, Sharp F, Rogers K (1997) Skin appendage involvement in anal intraepithelial neoplasia. Br J Surg, 84: 675–678
Ständer S, Weisshaar E, Mettang T, Szepietowski JC, Carstens E, Ikoma A, Bergasa N, Gieler U, Misery L, Wallengren J, Darsow U, Streit M, Metze D, Luger TA, Greaves MW, Schmelz M, Yosipovitch G, Bernhard J (2007) Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Dermatol Venerol 87: 291–294
Stevens HP, Ostlere LS, Rustin MH (1993) Perianal bowenoid papulosis presenting with pruritus ani. Br J Dermatol 129: 648–649
Stockfleth E, Beti H, Orasan R, Grigorian F, Mescheder A, Tawfik H, Thielert C (2008) Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial. Brit J Dermatol 158:1329–1338
Thirlby RC, Hammer CJ, Galagan KA et al. (1990) Perianal paget’s disease: successful treatment with combined chemoradiotherapy. Dis Col Rect 33: 150–152
Thornton JP, Abcarian H (1978) Surgical treatment of perianal hidradenitis suppurativa. Dis Colon Rectum 21: 573–577
Tolia M, Tsoukalas N, Sofoudis C, Giaginis C, Spyropoulou D, Kardamakis D, Kouloulias V, Kyrgias G (2016) Primary extramammary invasive Paget’s vulvar disease: what is the standard, what are the challenges and what is the future for radiotherapy? BMC Cancer 29 16: 563
van der Zee HH, Prens EP, Boer J (2010) Deroofing: a tissue-saving surgical technique for the treatment of mild to moderate hidradenitis suppurativa lesions. J Am Acad Dermatol 63: 475–480
van der Zee HH, de Ruiter L, van den Broecke DG, Dik WA, Laman JD, Prens EP (2011) Elevated levels of tumour necrosis factor (TNF)-alpha, interleukin (IL)-1beta and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-alpha and IL-1beta. Brit J Dermatol 164: 1292–1298
Velpeau A (1839) Aissele. In: Behcet J (ed) Dictionnaire de médicine, un répertoire général des sciences médicales sons la rapport théorétique et pratique, vol II, p 91
Verneuil AS (1854) Etudes sur les tumours de la peau et quelques maladies de glandes sudoripares. Arch Gen Med 94: 693–705
von der Werth JM, Jemec GB (2001) Morbidity in patients with hidradenitis suppurativa. Brit J Dermatol 144: 809–813
Wagner G, Rose C, Sachse MM (2013) Clinical variants of lichen planus. J Dtsch Dermatol Ges 11: 309–319
Weber H, Wolfram S (1967) Zoster sacralis mit Beteiligung der Harnblase. Wien Med Wochenschr 117: 670
Weyandt GH, Benoit S, Becker JC, Brocker EB, Hamm H (2005) Controlled layered removal of anogenital warts by argon-plasma coagulation. J Dtsch Dermatol Ges 3: 271–275
Weyandt GH, Vetter-Kauczok CS, Becker JC, Bröcker EB, Hamm H (2007) Successful dexamethasone pulse therapy for widespread erosive perianal lichen planus. Hautarzt 58: 241–242, 244–245
White WB, Hanna M, Stewart JA (1984) Systemic herpes simplex virus type 2 infection. Proctitis, urinary retention, arthralgias and meningitis in the absence of primary mucocutaneous lesions. Arch Intern Med 144: 826–827
Wieland U, Kreuter A (2015) HPV-induced anal lesions. Hautarzt 66: 439–445. doi: 10.1007/s00105-015-3630-0
Wieland U, Kreuter A (2017) Kondylome bei HIV Infizierten, Hautarzt 68: 192. doi:10.1007/s00105-017-3938-z
Wienert V (2012) Dermatologische Erkrankungen des Anorekturms. In: Lange J, Mölle B, Girona J (Hrsg) Chirurgische Proktologie, 2. Aufl. Springer, Berlin Heidelberg
Wienert V, Grußendorf E (1980) Anokutaner Ergotismus gangraenosus. Hautarzt 31: 668–670
Wiltz O, Schoetz DJ, Murray JJ, et al. (1990) Perianal hidradenitis suppurativa. The Lahey experience. Dis Colon Rectum 33: 731–734
Wolters W (2012) Zum Entartungsrisiko des Lichen sclerosus. Pink & Blue, Zeitschrift des Zentrums für Dermatopathologie Freiburg. 27: 21–35
Xu H, Xiao X, Hui Y, et al. (2016) Phenotype of 53 Chinese individuals with nicastrin gene mutations in association with familial hidradenitis suppurativa (acne inversa). Brit J Dermatol 174: 927–929
Yaghoobi R, Makvandi M, Afshar N, Pazyar N, Hamidifard M, Sharifpour C (2015) High Frequency of Human Papillomavirus Genotype 16 Among Patients With Anogenital Warts. Jundishapur J Microbiol 8: e25882. doi:10.5812/jjm.25882
Yang EJ, Quick MC, Hanamornroongruang S, Lai K, Doyle LA, McKeon FD, Xian W, Crum CP, Herfs M (2015) Microanatomy of the cervical and anorectal squamocolumnar junctions: a proposed model for anatomical differences in HPV-related cancer risk. Mod Pathol 28: 994–1000. doi: 10.1038/modpathol.2015.54
Zouboulis CC, Bechara FG, Fritz K, et al. (2012) S1 guideline for the treatment of hidradenitis suppurativa/acne inversa (number ICD-10 l73.2). JDDG 10 (Suppl 5): S1–31
Author information
Authors and Affiliations
Corresponding authors
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer-Verlag GmbH Deutschland
About this chapter
Cite this chapter
Weyandt, G., Bauer, B. (2018). Dermatologische Erkrankungen des Anorektums. In: Mölle, B., Ommer, A., Lange, J., Girona, J. (eds) Chirurgische Proktologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54682-6_12
Download citation
DOI: https://doi.org/10.1007/978-3-662-54682-6_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-54681-9
Online ISBN: 978-3-662-54682-6
eBook Packages: Medicine (German Language)