Zusammenfassung
Bakterien können für den Menschen krankmachende (pathogene Bakterien, Infektionserreger) oder schützende Eigenschaften (apathogene und fakultativ pathogene Bakterien der Mikrobiota) haben. Der Verlauf und der Typ einer bakteriellen Infektionskrankheit hängt ab von den Pathogenitätsfaktoren des Erregers und dem Infektionsabwehrpotenzial des Wirtes. Hier werden die evolutionären und pathogenetischen Aspekte bakterieller Erreger dargestellt im Kontext der Wirtsabwehrmechanismen. Die diskutierten Konzepte und mechanistischen Prinzipien der Erregerpathogenität sollen dazu beitragen, die infektionsmedizinischen Strategien in der Diagnostik, Therapie und Prävention von Infektionskrankheiten besser zu verstehen bzw. dem neuesten Wissensstand anzupassen.
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Heesemann, J. (2016). Pathogenität und Virulenz. In: Suerbaum, S., Burchard, GD., Kaufmann, S., Schulz, T. (eds) Medizinische Mikrobiologie und Infektiologie. Springer-Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48678-8_3
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DOI: https://doi.org/10.1007/978-3-662-48678-8_3
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