Abstract
Lanthanide-doped upconversion nanoparticles (UCNPs) possess unique anti-Stokes optical properties, in which low-energy near-infrared (NIR) excitation can be converted into high-energy UV and/or visible emission with pronounced luminescence and chemical stability. Due to the rapid development of synthesis chemistry, lanthanide-doped UCNPs can be fabricated with narrow distribution and modulated physical behaviors. These unique characters endow them unique NIR-driven imaging/delivery/therapeutic applications, especially in the cases of the deep tissue environments. Herein, we introduce both the basic concepts and the up-to-date progresses of UCNPs in material engineering, toxicology, and bio-applications in imaging, molecular delivery, and tumor therapeutics.
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Li, Z., Zhang, Y., Han, G. (2016). Lanthanide-Doped Upconversion Nanoparticles for Imaging-Guided Drug Delivery and Therapy. In: Dai, Z. (eds) Advances in Nanotheranostics I. Springer Series in Biomaterials Science and Engineering, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48544-6_4
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DOI: https://doi.org/10.1007/978-3-662-48544-6_4
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