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ART for Antiaging

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Artemisinin and Nitric Oxide

Part of the book series: SpringerBriefs in Molecular Science ((BRIEFSMOLECULAR))

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Abstract

ART can mimic CR to extend yeast lifespan, during which both ART and CR-triggered NO can activate antioxidative responses and convert the metabolic pattern from biosynthesis to degradation. ART also mimics CR to compromise mouse telomere shortening by upregulating antioxidative enzymes for effective ROS scavenging, which is followed by the alleviation of DNA damage and downregulation of tumor suppressors. This is the first time for having found ART exerting an antiaging role.

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  1. Tropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, China

    Qing-Ping Zeng

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Zeng, QP. (2015). ART for Antiaging. In: Artemisinin and Nitric Oxide. SpringerBriefs in Molecular Science. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47688-8_6

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