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Artemisinin and Nitric Oxide

Part of the book series: SpringerBriefs in Molecular Science ((BRIEFSMOLECULAR))

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Abstract

ART has been found, for the first time, to alkylate the heme-containing enzymes (hemoenzymes) by covalently conjugating the prosthetic heme. A high dose of ART can kill cancer cells and bacteria through compromising protective NO production. A low dose of ART can mimic CR to extend lifespan and reduce weight by triggering mitochondrial biogenesis. Therefore, ART can exert versatile beneficial effects on human health in addition to antimalaria.

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Authors and Affiliations

  1. Tropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, China

    Qing-Ping Zeng

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  1. Qing-Ping Zeng
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Correspondence to Qing-Ping Zeng .

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Zeng, QP. (2015). Background. In: Artemisinin and Nitric Oxide. SpringerBriefs in Molecular Science. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47688-8_1

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