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Terpenes and Essential Oils as Skin Penetration Enhancers

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Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement

Abstract

Percutaneous drug delivery is beset with an outstanding and inevitable challenge in the form of the stratum corneum – a natural skin barrier which regulates the influx of foreign substances into the body. One of the classical approaches used to mitigate this barrier is the use of chemical penetration enhancers. Terpenes and essential oils are one of the most effective and safe class of chemical penetration enhancers and are classified under generally regarded as safe (GRAS) category by US full name (Food and Drug Administration). This chapter presents an overview of the research ventures dedicated to the application of terpenes and essential oils as sorption promoters in pursuit of improved and accentuated drug delivery via percutaneous route.

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Authors and Affiliations

  1. Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi, 110062, India

    Jayamanti Pandit, Mohammed Aqil & Yasmin Sultana

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  1. Jayamanti Pandit
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  2. Mohammed Aqil
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  3. Yasmin Sultana
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Correspondence to Mohammed Aqil .

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Editors and Affiliations

  1. Department of Manufacturing, Apoteka "Beograd", Belgrade, Serbia

    Nina Dragicevic

  2. Dermatology Clinic, University of California San Francisco Dermatology Clinic, San Francisco, USA

    Howard I. Maibach

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Pandit, J., Aqil, M., Sultana, Y. (2015). Terpenes and Essential Oils as Skin Penetration Enhancers. In: Dragicevic, N., Maibach, H. (eds) Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47039-8_11

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