Zusammenfassung
Pharmakokinetik beschreibt die Aufnahme (Absorption), Verteilung (Distribution), den Metabolismus und die Ausscheidung (Exkretion), abgekürzt ADME, von Pharmaka. Pharmaka können auch in tiefen Kompartimenten gespeichert werden. Erklärt werden in diesem Kapitel außerdem quantitative Parameter wie Halbwertszeit, Eliminationskonstante, Verteilungsvolumen, Clearance, Sättigungsdosis und Erhaltungsdosis, Kumulationsfaktor, absolute und relative Bioverfügbarkeit.
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Freissmuth, M. (2016). Pharmakokinetik. In: Pharmakologie und Toxikologie. Springer-Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46689-6_2
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DOI: https://doi.org/10.1007/978-3-662-46689-6_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-46688-9
Online ISBN: 978-3-662-46689-6
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