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Autoinflammatory Syndromes: Relevance to Inflammatory Skin Diseases and Personalized Medicine

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Personalized Treatment Options in Dermatology

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Abstract

The main monogenic autoinflammatory syndromes are reviewed and their relevance to the understanding and treatment of sporadic and complex disorders, is discussed. Diseases addressed in this chapter include CAPS, DIRA, FMF, PAPA syndrome, CANDLE syndrome, AOSD and Schnitzler’s syndrome. The comprehension of the pathogenetic mechanisms of these autoinflammatory disorders has profoundly changed the nosology of inflammatory disorders. It has opened the path to a sign based, personalized approach to the patient with an inflammatory disorder, allowing optimized treatment and avoiding unnecessary overtreatment.

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Author information

Authors and Affiliations

  1. Department of Dermatology, Faculté de Médecine, Université de Strasbourg et Clinique Dermatologique, Hôpitaux Universitaires, Strasbourg, 67000, France

    Dan Lipsker MD, PhD

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  1. Dan Lipsker MD, PhD
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Correspondence to Dan Lipsker MD, PhD .

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Editors and Affiliations

  1. Department of Dermatology and Allergy, Center of Translational Medicine, University of Bonn, Bonn, Germany

    Thomas Bieber

  2. St. John's Institute of Dermatology, London, United Kingdom

    Frank Nestle

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Lipsker, D. (2015). Autoinflammatory Syndromes: Relevance to Inflammatory Skin Diseases and Personalized Medicine. In: Bieber, T., Nestle, F. (eds) Personalized Treatment Options in Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45840-2_7

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  • DOI: https://doi.org/10.1007/978-3-662-45840-2_7

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-45839-6

  • Online ISBN: 978-3-662-45840-2

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