Abstract
Leptospira was isolated and identified as the causative agent of the severe human syndrome Weil’s disease about 100 years ago almost simultaneously, but independently, by workers in Japan and Europe. Since that time leptospires have been isolated from almost all mammalian species on every continent except Antarctica, with leptospirosis now recognized as the most widespread zoonosis worldwide and also a major cause of disease in many domestic animal species. Recent advances in molecular taxonomy have facilitated the development of a rational classification system, while the availability of genome sequences and the development of mutagenesis systems have begun to shed light on mechanisms of pathogenesis that appear to be unique to Leptospira.
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References
Adler B, de la Peña Moctezuma A (2010) Leptospira and leptospirosis. Vet Microbiol 140:287–296
Alston JM, Broom JC (1958) Leptospirosis in man and animals. E & S Linvingstone, Edinburgh
Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, Levett PN, Gilman RH, Willig MR, Gotuzzo E, Vinetz JM (2003) Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis 3:757–771
Ellis WA (1990) Leptospirosis; a review of veterinary aspects. Ir Vet News 12:6–12
Faine S, Stallman ND (1982) Amended descriptions of the genus Leptospira Noguchi 1917 and the species L. interrogans (Stimson 1907) Wenyon 1926 and L. biflexa (Wolbach and Binger 1914) Noguchi 1918. Int J Syst Bacteriol 32:461–463
Faine S, Adler B, Bolin C, Perolat P (1999) Leptospira and leptospirosis. Medisci, Melbourne
Gouveia EL, Metcalfe J, de Carvalho AL, Aires TS, Villasboas-Bisneto JC, Queirroz A, Santos AC, Salgado K, Reis MG, Ko AI (2008) Leptospirosis-associated severe pulmonary hemorrhagic syndrome, Salvador, Brazil. Emerg Infect Dis 14:505–508
Hovind-Hougen K (1979) Leptospiraceae, a new family to include Leptospira Noguchi 1917 and Leptonema gen. nov. Int J Syst Bacteriol 29:245–251
Hubener R (1915) Beitrage zur Aetiologie der Weischen Krankheit. Mitt I. Deut Med Wochenschr 41:1275
Ido Y, Hoki R, Ito H, Wani H (1917) The rat as a carrier of Spirochaeta icterohaemorrhagiae, the causative agent of Spirochaetosis icterohaemorrhagica. J Exp Med 26:341–353
Inada R, Ido Y, Hoki R, Kaneko R, Ito H (1916) The etiology, mode of infection, and specific therapy of Weil’s disease (Spirochaetosis Icterohaemorrhagica). J Exp Med 23:377–402
Kitamura H, Hara H (1918) Ueber den Erreger von “Akiyami”. Tokyo Med J 2056/57
Klarenbeek A, Schuffner W (1933) Het verkomen van een afwijkend Leptospira-ras in Nederland. Ned Tijdschr Geneeskd 77:4271–4276
Levett PN, Morey RE, Galloway R, Steigerwalt AG, Ellis WA (2005) Reclassification of Leptospira parva Hovind-Hougen et al 1982 as Turneriella parva gen nov. comb. nov. Int J Syst Evol Microbiol 55:1497–1499
Marshall RB (1992) International committee on systematic bacteriology subcommittee on the taxonomy of Leptospira: minutes of the meetings, 13 and 15 September 1990, Osaka, Japan. Int J Syst Bacteriol 42:330–334
Noguchi H (1917) Spirochaeta icterohaemorrhagiae in American wild rats and its relation to the Japanese and European strains: first paper. J Exp Med 25:755–763
Noguchi H (1918) Morphological characteristics and nomenclature of Leptospira (Spirochaeta) icterohaemorrhagiae (Inada and Ido). J Exp Med 27:575–592
Noguchi H (1928) The spirochetes. In: Jordan EO, Falk IS (eds) The newer knowledge of bacteriology and immunology. University of Chicago Press, Chicago, pp 452–497
Semskov MV (1940) To the materials on etiology of infectious yellow fever of cattle. Sovet Vet 6:22–23
Stimson AM (1907) Note on an organism found in yellow-fever tissue. Pub Health Rep (Washington) 22:541
Stokes A, Ryle JA, Tytler WH (1917) Weil’s disease (Spirochaetosis ictero-haemorrhagica) in the British army in Flanders. The Lancet 189:142–153
Uhlenhuth P, Fromme W (1915) Experimentelle Untersuchen uber die sogenannte Weilsche Krankheit. Med Klin (Munchen) 44:1202
van Thiel PH (1948) The leptospiroses. Universitaire Pers Leiden, Leiden
Weil A (1886) Ueber einer eigenhuemliche, mit Milztumor, Icterus un Nephritis einhergehende, acute Infektionskrankheit. Deutsch Arch Klin Med 39:209
Wolbach SC, Binger CAL (1914) Notes on a filterable spirochete from frech water. Spirochaeta biflexa (new species). J Med Res 30:23–25
Yasuda PH, Steigerwalt AG, Sulzer KR, Kaufmann AF, Rogers F, Brenner DJ (1987) Deoxyribonucleic acid relatedness between serogroups and serovars in the family Leptospiraceae with proposals for seven new Leptospira species. Int J Syst Bacteriol 37:407–415
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Adler, B. (2015). History of Leptospirosis and Leptospira . In: Adler, B. (eds) Leptospira and Leptospirosis. Current Topics in Microbiology and Immunology, vol 387. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45059-8_1
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