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Inhibitory Action of the Purkinje Cell Axons

  • Chapter
The Cerebellum as a Neuronal Machine

Abstract

The anatomical aspects of the efferent cerebellar systems have been discussed by Jansen and Brodal (1954, 1958) on the basis of a comprehensive review of the literature and of the great wealth of their own experimental material. Lacking experience of our own, very little if anything could be added to these excellent reviews and apart from that they are largely outside the scope of this monograph. From the viewpoint of the general understanding of the cerebellar machinery, the general conclusion is important, that the cerebellar cortex has a clear sagittal projection from the medial cortical zone (the vermis) to the fastigial nuclei, from the adjacent intermediate zones on each side to the interpositus nuclei and from two lateral zones to the lateral (dentate) nuclei (Jansen and Brodal, 1940). Clear physiological equivalents of this somatotopic arrangement have been demonstrated by Chambers and Sprague (1955 a,b). The pathways for the next stage of conduction are less simply organized. While the efferent tracts of the fastigial nuclei are distributed predominantly in the medulla oblongata, the efferents originating from the interpositus and lateral nuclei project mainly to the midbrain and the thalamus. For details of these projections the monograph (1954) and review (1958) of Jansen and Brodal have to be consulted.

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Authors and Affiliations

  1. Institute for Biomedical Research, American Medical Association, Education and Research Foundation, 535 North Dearborn Street, 606 10, Chicago, Ill., USA

    Professor Dr. John C. Eccles

  2. University of Tokyo, Japan

    Dr. Masao Ito (Associate Professor of Physiology Faculty of Medicine)

  3. Department of Anatomy University Medical School, Tüzoltó utca 58, Budapest, IX., Hungary

    Professor Dr. János Szentágothai

Authors
  1. Professor Dr. John C. Eccles
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  2. Dr. Masao Ito
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  3. Professor Dr. János Szentágothai
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Eccles, J.C., Ito, M., Szentágothai, J. (1967). Inhibitory Action of the Purkinje Cell Axons. In: The Cerebellum as a Neuronal Machine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13147-3_14

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  • DOI: https://doi.org/10.1007/978-3-662-13147-3_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-13149-7

  • Online ISBN: 978-3-662-13147-3

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