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Therapie kardiovaskulärer Erkrankungen

  • Chapter
Praktische Arzneitherapie

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Zusammenfassung

Diese Medikamentengruppe wird eingesetzt um erhöhte Blutdruckwerte (>140/90 mg/Hg) zu senken bzw. zu normalisieren. Es handelt sich bei der medikamentösen antihypertensiven Behandlung um eine symptomatische, aber nicht um eine kausale Therapie. Die Kooperation der Patienten (Compliance) ist Voraussetzung, um auf lange Sicht die Hypertonie zu kontrollieren und deren kardiovaskuläre und renale Komplikationen zu verhindern. Beginn, Absetzen oder die Dosisanpassung einer antihypertensiven Therapie sollten niemals ohne ärztliche Überwachung erfolgen, wobei Arzt und Patient auf rechtzeitige Wiederverschreibung der Medikation achten müssen (Vermeidung eines „Rebound-Phänomens“). Arzneimittelwechselwirkungen von Antihypertensiva mit gleichzeitig verabreichten Pharmaka sind zahlreich und können zur Wirkabschwächung (z. B. nichtsteroidale Antirheumatika) oder zur Wirkverstärkung der blutdrucksenkenden Medikamente führen (z. B. bei gleichzeitiger Gabe weiterer antihypertensiver Substanzen, von Nitraten oder Neuroleptika). An Nebenwirkungen verursachen Antihypertensiva häufig Müdigkeit, Schwindel und Benommenheit, sodass die Fahrtüchtigkeit und Tätigkeiten, die erhöhte geistige Aufmerksamkeit erfordern, beeinträchtigt werden können. Gleichzeitiger Alkoholgenuss bzw.

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  1. W. Kirch
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  1. Institut für Klinische Pharmakologie, Medizinische Hochschule Hannover, D-30623, Hannover, Deutschland

    J. C. Frölich

  2. Medizinische Fakultät, Institut für Klinische Pharmakologie, Technische Universität Dresden, Fiedlerstr. 27, D-01307, Dresden, Deutschland

    W. Kirch

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© 2000 Springer-Verlag Berlin Heidelberg

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Kirch, W. (2000). Therapie kardiovaskulärer Erkrankungen. In: Frölich, J.C., Kirch, W. (eds) Praktische Arzneitherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09398-6_12

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  • DOI: https://doi.org/10.1007/978-3-662-09398-6_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66071-2

  • Online ISBN: 978-3-662-09398-6

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