Zusammenfassung
Unabhängig davon, ob bakterielle Toxine oder andere primär nicht bakterielle Aggressionen Auslöser für eine schließlich generalisierte Entzündungsreaktion des Organismus sind, immer werden die gleichen lebenswichtigen Kaskadensysteme angeregt:
-
das Komplementsystem,
-
das Gerinnungs-Fibrinolyse-System,
-
das Kallikrein-Kinin-System.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Asanuma Y, Takahashi T, Kato T, Kudo K, Koyama K (1989) Treatment of endotoxin shock due to gram-negative bacteremia using extracorporal circulation. Nippon Shokakibyo Gakkai Zasshi 86: 246–252
Asanuma Y, Takahashi T, Koyama K, Kato T, Omokawa S, Sueoka A, Tanaka J (1989) Exchange blood transfusion and on-line plasma exchange for sepsis in infants. ASAIO Trans 35: 343–345
Bambauer R, Meyer S, Jung H, Goehl H, Nystrand R (1990) Sterile versus non-sterile dialysis fluid in chronic hemodialysis treatment. ASAIO Trans 36: 317–320
Barckow D, Schirop T (1983) Isolierte Ultrafiltration beim akuten Lungenversagen. Intensivmed 20: 213–216
Barzilay E, Kessler D, Berlot G, Gullo A, Geber D, Ben Zeev I (1989) Use of extracorporeal supportive techniques as additional treatment for multiple organ failure patients. Crit Care Med 17: 634–637
Baumann J, Kiene S, Kampfer I, Hofmann J (1991) Animal experiment studies of the distribution and elimination of marked endotoxin. Zentralbi Chir 116: 969–981
Baurmeister U, Travers M, Vienken J, Harding G, Million C, Klein E, Pass T (1989) Dialysate contamination and back filtration may limit the use of high-flux dialysis membranes. ASAIO Trans 35: 519–522
Bende S, Bertok L (1986) Elimination of endotoxin from the blood by extracorporeal activated charcoal hemoperfusion in experimental canine endotoxin shock. Circulatory Shock 19: 239–244
Beutler B, Cerami A (1987) The biology of cachectin/TNF–a primary mediator of the host response. Ann Rev Immunol 7: 625–655
Bjorvatn B, Bjertnaes L, Fadnes HO et al. (1984) Meningokoccal septicaemia treated with combined plasmapheresis and leucapheresis or with blood exchange. Br Med J 288: 439441
Bone RC, Balk RA, Cerra FB et al. (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101: 1644–1655
Bozkurt F, Hörl WH (1987) Bedeutung der kontinuierlichen arteriovenösen Hämofiltration (CAVA) and arteriovenösen Hämodiafiltration ( AV-HDF) in der Intensivtherapie. Intensivmed 24: 248–254
Brigham KL, Meyrick B (1986) Endotoxin and lung injury. Am Rev Respir Dis 133: 913927
Brunet P, Jaber K, Berland V, Baz M (1992) Anaphylactoid reactions during hemodialysis and hemofiltration: role of AN69 membrane and angiotensin I-converting enzyme inhibitors. Am J Kidney Dis 19: 444–447
Bysani GK, Shenep JL, Hildner WK, Stidham GL, Roberson PK (1990) Detoxification of plasma containing lipopolysaccharide by adsorption. Crit Care Med 18: 67–71
Carozzi S, Nasini MG, Caviglia PM, Schelotto C, Santoni O, Atti M (1992) Acetetate free biofiltration. Effects on peripheral blood monocyte activation and cytokine release. ASAIO Trans 38: 52–54
Cheadle WG, Hanasawa K, Gallinaro RN, Nimmanwudipong T, Kodama M, Polk HC Jr (1991) Endotoxin filtration and immune stimulation improve survival from sepsis. Surgery 110: 785–791
Colton CK (1987) Analysis of membrane processes for blood purification. Blood Purif 5: 202–251
Coraim F, Pongratz-Coraim H, Mauritz W, Ebermann R (1986) Hämofiltration als Therapie des akuten Lungenversagens im kardiogenen Schock. Anaesthesist 35: 187–192
Diez T (1983) Untersuchungen zur Elimination von Endotixin in vitro. Inauguraldissertation, Berlin
Dobos GJ, Meske S, Keller E, Riegel W, Vaith P, Peter HH, Schollmeyer P (1990) Successful therapy of meningococcal sepsis in acute disseminated lupus with plasmapheresis, immunosuppression and antibiotics. Klin Wochenschr 68: 976–980
Fisher CJ, Panacek EA (1989) Toxic shock syndrome. In: Shoemaker WC, Ayres S, Grenvik A, Holbrook RR, Thompson WL (eds) Textbook of critical care. Saunders, Philadelphia London Tokyo
Golper TA, Jenkins R, Wright M, Klein JB (1990) Tumor necrosis factor ( TNF) and hemofiltration membranes. Intensivbehandlung 15: 119
Gomez A, Wang R, Unruh H et al. (1990) Hemofiltration reverses left ventricular dysfunction during sepsis in dogs. Anesthesiology 73: 671–685
Gotloib L, Barzilay E, Shustak A, Wais Z, Jaichenko J, Lev A (1986) Hemofiltration in septic ARDS. The artificial kidney as an artificial endocrine lung. Resuscitation 13: 123132
Graben N (1980) Entgiftung mit Hämoperfusion. Bindernagel, Friedberg
Groeneveld ADJ (1990) Septic shock and multiple organ failure: treatment with hemofiltration? Intensive Care Med 16: 489–490
Hanasawa K, Aoki H, Yoshioka T, Matsuda K, Tani T, Kodama M (1989) Novel mechanical assistance in the treatment of endotoxic and septicemic shock. ASAIO Trans 35: 341–343
Hanasawa K, Tani T, Kodama M (1989) New approach to endotoxic and septic shock by means of polymyxin B immobilized fiber. Surg Gynecol Obstet 168: 323–331
Hogquist KA, Unanue ER, Chaplin DD (1991) Release of IL-1 from mononuklear phagocytes. J Immunol 147: 2181–2186
Koller WF, Benzer HM, Pauser GF (1985) CAVH in acute respiratory failure. In: Sieberth HG, Mann H (eds) Continuos arteriovenous remofiltration (CAVH). Karger, Basel
Klinkmann H, Falkenhagen D, Smollich BP (1985) Investigation of the permeability of highly permeable polysulfone membranes for pyrogens. Karger, Basel (Contr Nephrol, vol 46, pp 147–183 )
Kramer P, Wigger W, Rieger J, Matthhai D, Scheler F (1977) Arteriovenous haemofiltration: a new and simple method for treatment of over-hydrated patients resistant to diuretics. Klin Wochenschr 55: 1121–1122
Luderitz O, Galanos C, Lehmann V et al. (1973) Lipid A: Chemical structure and biological activity. J Infect Dis 128 (Suppl): S17 - S29
Mauritz W, Sporn P, Schindler I, Zadrobilek E, Roth E, Appel W (1986) Akutes Nierenversagen bei abdomineller Sepsis. Anästh Intensivther Notfallmed 21: 212–217
May LT, Santhanam U, Sehgal PB (1991) On the multimeric nature of natural human Interleukin-6. J Biol Chem 266: 9950–9955
McCelland P, Williams PS, Yagoob M, Mostafa SM, Bone JM (1990) Multiple organ failure: a role for plasma exchange? Intensive Care Med 16: 100–103
Nakamura Y, Wakabayashi A, Wolley T, Mullin P, Ito Y, Connolly JE (1976) Total body washout for the treatment of endotoxin shock. Arch Surg 111: 783–786
Nemes C, Niemer M (1992) Blutreinigungsverfahren. In: Niemer M, Nemes C, Lundsgaardhansen P, Blauhuth B (Hrsg) Datenbuch Intensivmedizin. Fischer, Stuttgart Jena New York
Nieter B, Sisova S, Klug C et al. (1991) Plasmaaustausch bei septisch-toxischen Krankheitsbildern. Nieren-/Hochdruckkrankh 20: 155–159
Nisbeth U, Hallgren R, Eriksson O, Danielson BG (1987) Endotoxemia in chronic renal failure. Nephron 45: 93–97
Olbricht CJ (1992) Pharmakotherapie bei kontinuierlicher Hämofiltration. Intensivmed 29: 4–8
Ossenkoppele GJ, Meulen J van der, Bronsveld W, Thijs LG (1985) Continous arteriovenous hemofiltration as an adjunctive therapy for septic shock. Crit Care Med 13: 102–104
Osterud B (1985) Meningococcal septicemia: the use of plasmapheresis or blood exchange and how to detect severe endotoxin induced white cell activation. Scand J Clin Lab Invest (Suppl) 178: 47–51
Pegues AS, Sofer SS, McCallum RE, Hinshaw LB (1979) The removal of C14 labeled endotoxin by activated charcoal. Int J Artef Org 2: 153–158
Pusey CD, Aslam M, Cohen J, Courtney JM, Ryan CJ (1991) Experimental models of plasma perfusion. J Clin Apher 6: 99–102
Rietschel ET, Brade H (1987) Lipopolysaccharide, die Endotoxine und 0-Antigene gramnegativer Bakterien: Chemische Struktur, biologische Wirkung und serologische Eigenschaften. Infection 15: 576–584
Röckel A, Abdelhamid S, Fliegel P, Walb D (1985) Elimination of low molecular weight proteins with high flux membranes. Contr Nephrol 46: 69–74
Sawada K, Malchesky PS, Nose Y (1990) Available removel systems: State of the art. In: Nydegger VE (ed) Therapeutic Hemapheresis in the 1990’s. Karger, Basel (Curr Stud Hematol Blood Transfus 57: 51–113 )
Schwerdtfeger R (1993) Verhalten der Plasmoproteine bei verschiedenen Methoden der therapeutischen Plasmapherese: Untersuchungen zur Notwendigkeit von Sekundärsystemen. Habilitationsschrift, Berlin
Sieberth HG (1982) Apparative Detoxikation: Plasmaseparation. Intensivmed 19: 74–78
Staubach KH, Rau HG, Kooistra A, Schardey HM, Hohlbach G, Schilberg FW (1989) Can hemofiltration increase survival time in acute endotoxemia–a porcine shock model. Prog Clin Biol Res 308: 821–826
Steel CM, Hutchins D (1989) Soluble factors and cell-surface moleculs involved in human B lyphocyte activation, growth and differentiation. Biochem Biophys Acta 989: 133–151
Stein B, Pfenninger E, Grunert A, Schmitz JE, Deller A, Kocher F (1991) The consequences of continous haemofiltration on lung mechanics and extravascular lung water in a porcine endotoxic shock model. Intensive Care Med 17: 293–298
Stokes DC, Shenep JL, Fishman M (1989) Polymyxin B prevents lipopolysaccharid induced release of tumor necrosis faktor-alpha from alveolare macrophages. J Infect Dis 160: 52–57
Storck M, Hartl WH, Zimmerer E, Inthorn D (1991) Comparison of pump-driven and spontaneous continuous haemofiltration in postoperative acute renal failure. Lancet 337: 452–455
Susini G, Zuccetti M, Bortone F, Salvi L, Cipolla CM, Rimondini A, Sisillo E (1990) Isolated ultrafiltration in cardiogenic pulmonary edema. Crit Care Med 18: 14–17
Tani T, Hanasawa K, Kodama M (1989) Usefulnes of endotoxic removal from the septic blood with direct hemoperfusion using PMX-F. Nippon Geka Gakkai Zasshi 90: 13701373
Tetta C, Camussi G, Turello E, Salomone M, Aimo G, Priolo G, Segoloni G (1990) Production of cytokines in hemodialysis. Blood Purif 8: 337–346
Vanholder R, Van Haecke E, Veys N, Ringoir S (1992) Endotoxin transfer through dialysis membranes: small versus large pore membranes. Nephrol Dial Transplant 7: 333–339
Wegmüller E (1981) Die therapeutische Bedeutung der Plasmapherese bei Immunkrankheiten. Schweiz Med Wochenschr 111: 443–449
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Barckow, D. (1993). Mediatorenelimination (Hämofiltration, Plasmapherese, Hämoperfusion). In: Schuster, HP. (eds) Intensivtherapie bei Sepsis und Multiorganversagen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07960-7_8
Download citation
DOI: https://doi.org/10.1007/978-3-662-07960-7_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-07961-4
Online ISBN: 978-3-662-07960-7
eBook Packages: Springer Book Archive