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Follicular Development and Apoptosis

  • Conference paper
The Future of the Oocyte

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 41))

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Abstract

More than 99.9% of the ovarian follicles present at birth never reach ovulation. The most common fate of follicles is instead to undergo atresia, which has been shown to be mediated by a highly organised type of cell death called apoptosis or programmed cell death (Hsueh et al. 1994; Billig et al. 1996; Kaipia and Hsueh 1997). The final tuning of the large number of growing follicles to a single ovulatory follicle is primarily achieved by cell death of granulosa cells (Hsueh et al. 1994; Reynaud and Driancourt 2000).

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Authors
  1. H. Billig
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  2. E. Markström
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  3. E. C. Svensson
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  4. R. Shao
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  5. A. Friberg
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Editor information

Editors and Affiliations

  1. The Jackson Laboratory, 600 Main Street, 04609, Bar Harbor, ME, USA

    J. Eppig

  2. Safety Pharm. Mgmt., Schering AG, MĂĽllerstr. 178, 13342, Berlin, Germany

    Ch. Hegele-Hartung

  3. Female Health Care, Schering AG, MĂĽllerstr. 178, 13342, Berlin, Germany

    M. Lessl

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© 2002 Springer-Verlag Berlin Heidelberg

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Billig, H., Markström, E., Svensson, E.C., Shao, R., Friberg, A. (2002). Follicular Development and Apoptosis. In: Eppig, J., Hegele-Hartung, C., Lessl, M. (eds) The Future of the Oocyte. Ernst Schering Research Foundation Workshop, vol 41. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04960-0_3

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  • DOI: https://doi.org/10.1007/978-3-662-04960-0_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04962-4

  • Online ISBN: 978-3-662-04960-0

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