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FF-MAS and Its Role in Mammalian Oocyte Maturation

  • Conference paper
The Future of the Oocyte

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 41))

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Abstract

Fertilization of the mammalian oocytes completes the meiotic process that has been initiated at the time of oocyte formation in fetal life. The meiotic cell division is a prerequisite for sexual reproduction and constitutes a unique cell division not only to produce gametes but also to control the successful interaction of gametes. The pituitary hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are generally believed to control the overall regulation of ovarian physiology and thereby also control the processes of follicular growth, oocytes maturation, and follicle ovulation. The mechanism by which the oocytes are inhibited from resuming meiosis in the ovarian follicular environment has not been completely elucidated. The follicle fluid contains purines, e.g., hypoxanthine, that are considered to be important inhibitory substances of oocyte maturation (Downs 1993; Downs et al. 1985; Eppig et al. 1985).

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Authors
  1. C. Grøndahl
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Editors and Affiliations

  1. The Jackson Laboratory, 600 Main Street, 04609, Bar Harbor, ME, USA

    J. Eppig

  2. Safety Pharm. Mgmt., Schering AG, Müllerstr. 178, 13342, Berlin, Germany

    Ch. Hegele-Hartung

  3. Female Health Care, Schering AG, Müllerstr. 178, 13342, Berlin, Germany

    M. Lessl

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© 2002 Springer-Verlag Berlin Heidelberg

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Grøndahl, C. (2002). FF-MAS and Its Role in Mammalian Oocyte Maturation. In: Eppig, J., Hegele-Hartung, C., Lessl, M. (eds) The Future of the Oocyte. Ernst Schering Research Foundation Workshop, vol 41. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04960-0_11

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  • DOI: https://doi.org/10.1007/978-3-662-04960-0_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04962-4

  • Online ISBN: 978-3-662-04960-0

  • eBook Packages: Springer Book Archive

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