Abstract
The biosynthesis and catabolism of phosphatidylcholine (PC) are tightly coupled processes. In the past decade significant progress has been made in unraveling control mechanisms for regulation of PC biosynthesis (Vance, 1990; Tijburg et al., 1989). In contrast the mechanisms that regulate PC catabolism are poorly understood. Renewed interest in regulation of PC catabolism has been sparked by the discovery that PC is a source of diacylglycerol, a second messenger that activates protein kinase C (Löffelholz, 1989; Exton, 1990). The purpose of the present chapter is to review the recent progress in these two areas of research with emphasis on the more recent contributions from the authors’ laboratory.
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© 1993 Springer-Verlag Berlin Heidelberg
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Vance, D.E. et al. (1993). Control of Phosphatidylcholine Metabolism. In: Massarelli, R., Horrocks, L.A., Kanfer, J.N., Löffelholz, K. (eds) Phospholipids and Signal Transmission. Nato ASI Series, vol 70. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02922-0_22
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DOI: https://doi.org/10.1007/978-3-662-02922-0_22
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