Zusammenfassung
Die Elongation von Axonen und aktive Modellierung ihrer Terminale stellt die Grundlage für die Entstehung neuraler Schaltkreise während der Entwicklung dar, determiniert Erfolg oder Mißerfolg neuraler Regeneration und trägt möglicherweise zu verchiedenen Formen synaptischer Plastizität im erwachsenen Zentralnervensystem bei. Die selektive Inaktivierung oder Retention des Axonwachstums in reifenden Nervenzellen mag sodann die Grenzen für regenerative Prozesse einschließlich der synaptischen Plastizität im adulten Zentralnervensystem verursachen.
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Wiese, U.H. (1996). Expression von Growth-associated-Protein (GAP-43) als Indikator neuroregenerativer Prozesse im Rückenmark. In: Gerner, HJ. (eds) Querschnittlähmungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-88030-8_2
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