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Biochemische, pharmakologische und humorale Aspekte des Schlaf-Wachseins

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Der Schlaf

Zusammenfassung

Eine Besprechung der neuen biochemischen und pharmakologischen Aspekte der Schlaf-Wach-Steuerung ist nur fruchtbar, wenn man sie in Beziehung zu den neurophysiologischen Fakten bringt. Durch eine solche Konfrontation lassen sich die neuralen und humoralen Regulationsmechanismen einheitlich erfassen.

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Literatur

  • Bowers M., Hartmann E. und Freedman D. X.: The effect of dream-deprivation on brain acetylcholine levels in the rat. Report to the Association for the Psychophysiological Study of Sleep. Gainesville (1966).

    Google Scholar 

  • Bradley P. B. und Elkes J.: The effect of amphetamine and D-lysergic acid diethylamide (LSD 25) on the electrical activity of the brain of the conscious cat. J. Physiol. (London) 120, 13P–14P (1953).

    CAS  Google Scholar 

  • Bradley P. B. und Key B. J.: The effect of drugs on arousal responses produced by electrical stimulation of the reticular formation of the brain. EEG clin. Neurophysiol. 10, 97–110 (1958).

    Article  CAS  Google Scholar 

  • Bradley P. B. und Nicholson A. N.: The effect of some drugs on hippocampal arousal. EEG clin. Neurophysiol. 14, 824–834 (1962).

    Article  CAS  Google Scholar 

  • Cordeau J. P., Moreau A., Beaulnes A. und Laurin C.: EEG and behavioral changes following micro-injections of acetylcholine and adrenaline in the brain stem of cats. Arch. Ital. Biol. 101, 30–47 (1963).

    PubMed  CAS  Google Scholar 

  • Creutzfeldt O. und Jung R.: Neuronal discharge in the cat’s motor cortex during sleep and arousal. In: The Nature of Sleep. CIBA Found. Symp. Ed. G. E. W. Wolstenholme and M. O’Connor. London, p. 131-170 (1961).

    Google Scholar 

  • Dawson R. M. C. und Richter D.; Effect of stimulation on the phosphate esters of the brain. Amer. J. Physiol. 160, 203–211 (1950).

    PubMed  CAS  Google Scholar 

  • Evarts E. V.: Effects of sleep and waking on activity of single units in the unrestrained cat. In: The Nature of Sleep. CIBA Found. Symp. Ed. G. E. W. Wolstenholme and M. O’Connor. London, p. 171-187 (1961).

    Google Scholar 

  • Favale E., Loeb C., Rossi G. F. und Sacco G.: EEG synchronization and behavioral signs of sleep following low frequency stimulation of the brain stem reticular formation. Arch. Ital. Biol. 99, 1–22 (1961).

    Google Scholar 

  • Gangloff H. und Monnier M.: Topic action of Reserpine, Serotonin and Chlorpromazine on the unanesthetized rabbit’s brain. Helv. Physiol. Acta 15, 83–104 (1957).

    CAS  Google Scholar 

  • Giarman N. J. und Schmidt K. F.: Some neurochemical aspects of the depressant action of γ-butyrolactone on the central nervous system. Brit. J. Pharmacol. and Chemotherap. 20, 563–568 (1963).

    CAS  Google Scholar 

  • Green H. und Sawyer J. L: Biochemical-pharmacological studies with 5-hydroxytryptophan, precursor of serotonin. In: Biogenic Amines. Ed. Humwich, Amsterdam (1964).

    Google Scholar 

  • Hayashi T.: Pavlov’s sleep theory under a new light. Keio J. Med. 14., 135–144 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Hernández-Peón R.: Neurophysiological mechanisms of wakefulness and sleep. Acta Neurol. Latinoamer. 10, 18–34 (1964).

    Google Scholar 

  • Hernández-Peón R.: Cholinergic and other humoral mechanisms: The problem of chemical specificity in the neural substratum of the sleep-wakefulness cycle. Neurosc. Res. Prog. Bull. 4, 43–47 (1966).

    Google Scholar 

  • Hess R., Akert K. und Koella W. P.: Cortical and subcortical recordings in natural and artificially induced sleep in cats. EEG clin. Neurophysiol. 5, 75–90 (1953).

    Article  Google Scholar 

  • Hess W. R.: Das Zwischenhirn als Koordinationsorgan. Helv. Physiol. Acta 1, 549–565 (1943).

    Google Scholar 

  • Hess W. R.: Das Schlafsyndrom als Folge diencephaler Reizung. Helv. Physiol. Acta 2, 305–344 (1944).

    Google Scholar 

  • Hösli L. und Monnier M.: Schlaf-und Weckwirkungen des intralaminären Thalamus. Reizparameter und Koagulationsbefunde beim Kaninchen. Pflügers Arch. 275, 439–451 (1962).

    Article  Google Scholar 

  • Hösli L. und Monnier M.: Wirkung der bilateralen Koagulation des mediozentralen intralaminären Thalamus auf die elektrische Hirnaktivität und das Verhalten des Kaninchens. Helv. Physiol. Acta 21, 109–113 (1963).

    Google Scholar 

  • Hösli L., Monnier M. und Koller Th.: Humoral transmission of sleep and wakefulness. I. Method for dialysing psychotropic humors from the cerebral blood. Pflügers Arch. 282, 54–59 (1965).

    Article  Google Scholar 

  • Hydén H. und Lange P. W.; Rhythmic enzyme changes in neurons and glia during sleep and wakefulness. In: Progress in brain research. Sleep mechanism. Amsterdam, Vol. 18, p. 92–95 (1965).

    Google Scholar 

  • Ilyutchenok R. J.: The role of cholinergic systems of the brain stem reticular formation in the mechanism of central effects of anticholinesterase and cholinolytic drugs. I. Int. Pharmacol. Meeting Oxford, London 8, 211–216 (1962).

    Google Scholar 

  • Ilyutchenok R. J.: Problems of chemical perceptibility of the brain stem reticular formation. Psychopharmacol. Methods, Prague, p. 115-122 (1963).

    Google Scholar 

  • Ilyutchenok R. J.: Hemato-encephalic barrier and EEG changes in effects of cholinergic substances. 6. Int. Congress EEG and Clin. Neurophysiol., Wien, p. 513-515 (1965).

    Google Scholar 

  • Ingvar D. und Soderberg U.: Cortical blood flow related to EEG patterns evoked by stimulation of the brain. Acta Physiol. Scand. 42, 130–143 (1958).

    Article  PubMed  CAS  Google Scholar 

  • Jeannerod M., Mouret J. und Jouvet M.: Etude de la motricité oculaire au cours de la phase paradoxale du sommeil chez le chat. EEG clin. Neurophysiol. 18, 554–566 (1965).

    Article  CAS  Google Scholar 

  • Jouvet M.: Telencephalic and rhombencephalic sleep in the cat. In: The Nature of Sleep. Ciba Found. Symp. Ed. G. E. W. Wolstenholme and M. O’Connor, London, p. 188-206 (1961).

    Google Scholar 

  • Jouvet, M.: Recherches sur les structures nerveuses et les mécanismes responsables des différentes phases du sommeil physiologique. Arch. Ital. Biol. 100, 125–206 (1962).

    PubMed  CAS  Google Scholar 

  • Jouvet M.: Paradoxical sleep — a study of its nature and mechanisms. In: K. Akert, C. Bally und J. P. Schadé: Progress in Brain Research, Vol. 18, p. 20-57, Amsterdam (1965).

    Google Scholar 

  • Jouvet M. und Jouvet D.: A study of the neurophysiological mechanisms of dreaming. EEG clin. Neurophysiol. Suppl. 24, 133–157 (1963).

    Google Scholar 

  • Jouvet M., Vimont P. und Delorme F.: Suppression élective du sommeil paradoxal chez le chat par les inhibiteurs de la monoamine oxydase. C. R. Soc. Biol. (Paris), 159, 1595–1599 (1965).

    CAS  Google Scholar 

  • Kanai T. und Szerb J. C.: Mesencephalic reticular activating system and cortical acetylcholine output. Nature 205, 80–82 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Kety S. S.: Sleep and the energy metabolism of the brain. In: The Nature of Sleep. CIBA Found. Symp. Ed. G. E. W. Wolstenholme and M. O’Connor, London, p. 375-381 (1961).

    Google Scholar 

  • Kikucki T.: Electroencephalographic studies on the action of reserpine, 2, 4-dihydroxyphenylalanine and 5-hydroxy-tryptophane in reference to the effects of pretreatment with β-phenylisopropylhydrazine. Japanese J. of Pharmacol, 11, 151–170 (1962).

    Article  Google Scholar 

  • Knapp D. R. und Domino E. F.: Species differences in the EEG response to epinephrine, 5-hydroxytryptamine and nicotine in brainstem transected animals. Int. J. Neuropharmacol. 2, 51–55 (1963).

    Article  CAS  Google Scholar 

  • Koella W. P.: Central EEG synchronizing effect of Serotonin. Neurosc. Res, Prog. Bull. 4, 47–49 (1966).

    Google Scholar 

  • Koella W. P., Trunca C. M. und Czicman J. S.: Serotonin: effect on recruiting responses of the cat. Life Sciences 4, 173–181 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Kramer S. Z. und Seifter J.: The effects of GABA and biogenic amines on behaviour and brain electrical activity in chicks. Life Sciences 5, 527–534 (1966).

    Article  CAS  Google Scholar 

  • Magnes J., Moruzzi G. und Pompeiano O.: Electroencephalogram — synchronizing structures in the lower brain stem. In: The nature of sleep. Ciba Found. Symp., London, p. 57-78. Ed. G. E. W. Wolstenholme and M. O’Connor (1961).

    Google Scholar 

  • Mahler D. J. und Humoller F. L.: The potentiation of hexobarbital hypnosis by 5-hydroxytryptamin. J. Neuropsychiat. 5, 252–258 (1964).

    PubMed  CAS  Google Scholar 

  • Matussek N. und Patschke U.: Beziehungen des Schlaf-und Wachrhythmus zum Noradrenalin-und Serotoningehalt im Zentralnervensystem von Hamstern. Med. exp. 11, 81–87 (1963).

    Google Scholar 

  • Monnier M.: Action de la stimulation électrique du centre somnogène sur l’électro-corticogramme chez le chat (Réactions hypniques et réaction d’éveil). Rev. Neurol. 83, 561–563 (1950).

    PubMed  CAS  Google Scholar 

  • Monnier M.: Topic action of psychotropic drugs on the electrical activity of cortex, rhinencephalon and mesodiencephalon (excitement, tranquillization, sedation and sleep). In: „Psychotropic Drugs“, Amsterdam (1957).

    Google Scholar 

  • Monnier M.: Actions électro-physiologiques des stimulants du système nerveux central. I. Systèmes adrénergiques, cholinergiques et neurohumeurs sérotoniques. Arch. Int. Pharmacodyn. 124, 281–301 (1960).

    PubMed  CAS  Google Scholar 

  • Monnier M.: Die Regulierung der Wach-und Schlafzustände als physiologisches Problem. Schweiz, med. Wschr. 49, 1406–1416 (1960).

    Google Scholar 

  • Monnier M.: Régulations nerveuses et humorales des activités vigiles et du sommeil. J. de Psychologie normale et pathologique 1, 1–31 (1965).

    Google Scholar 

  • Monnier M., Bhattacharya I. C. und Fallert M.: The waking action of Histamine. Experientia 23, 21–22 (1967).

    Article  PubMed  CAS  Google Scholar 

  • Monnier M. und S. Graber: Action de DOPA et du blocage de la monoaminoxydase par l’Iproniazid sur le cerveau. Schweiz. Arch. Neurol., Neurochir., Psychiat. 92, 410–414 (1963).

    CAS  Google Scholar 

  • Monnier M. und Hösli L.: Dialysis of sleep and waking factors in blood of the rabbit. Science 146, 796–298 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Monnier M., Koller Th. und Graber S: Humoral influences of induced sleep and arousal upon electrical brain activity of animals with crossed circulation. Exp. Neurol. 8, 264–277 (1963).

    Article  Google Scholar 

  • Monnier M. und Krupp P. (en coll. avec S. Graber): Classification électrophysiologique des stimulants du système nerveux central. II. Action des stimulants hallucinogènes, psychotoniques, analeptiques sur les mécanismes d’éveil et de détente. Arch. int. Pharmacodyn. 127, 337–360 (1960).

    PubMed  CAS  Google Scholar 

  • Monnier M. und Romanowski W.: Les systèmes cholinoceptifs cérébraux — Actions de l’acétylcholine, de la physostigmine, pilocarpine et de GABA. EGG clin. Neurophysiol. 14., 486–500 (1962).

    CAS  Google Scholar 

  • Monnier M. und Tissot R.: Correlated effects in behaviour and electrical brain activity evoked by stimulation of the reticular system, thalamus and rhinencephalon in the conscious animal. A CIBA Found. Symp.: On the Neurological Basis of Behaviour, London, p. 105-120 (1958).

    Google Scholar 

  • Moruzzi G.: Synchronizing influences of the brain stem and the inhibitory mechanisms underlying the production of sleep by sensory stimulation. In: Jasper H. H. and Smirnov G. D., Moscow Colloquium on EEG and higher nervous activity. EEG clin. Neurophysiol. Suppl. 13, 231–257 (1960).

    Google Scholar 

  • Moruzzi G. und Magoun H. W.: Brain stem reticular formation and activation of the EEG. EEG clin. Neurophysiol. 1, 455–473 (1949).

    CAS  Google Scholar 

  • Nosal Gl.: Unpubl.

    Google Scholar 

  • Pawlow J.: Innere Hemmung der bedingten Reflexe und der Schlaf — ein-und derselbe Prozeß. Skand. Arch. Physiol. 54, 42 (1923).

    Google Scholar 

  • Richter D. und Dawson R. M. C.: Brain metabolism in emotional excitement and in sleep. Amer. J. Physiol. 154, 73–79 (1948).

    PubMed  CAS  Google Scholar 

  • Rozanova V. D.: Kanalizu osobennostey i roli kholinergicheskoy i adrenergicheskoy substantsiy retikulyarnoy formatsii u sobak v razlichnye vozrastnye periody. (On the analysis of the role and nature of cholinergic and adrenergic substances of the reticular formation in dogs of various ages). Trudy Instituta: Instit Normal’ Noi i Pathologicheskoi Fitziologii, Akadennia Meditsingkikh Nauk SSR 7, 75–76 (1964).

    Google Scholar 

  • Sawyer Ch. H. und Kawakami M.: Characteristics of behavioral and electroencephalographic after-reactions to copulation and vaginal stimulation in the female Rabbit. Endocrinology 65, 622–630 (1959).

    Article  PubMed  CAS  Google Scholar 

  • Sterman M. B. und Clemente C. D.: Cortical recruitment and behavioral sleep induced by basal forebrain stimulation. Fed. Proc. 20, 334 (1961).

    Google Scholar 

  • Vogt M.: The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs. J. Physiol. 123, 451–481 (1954).

    PubMed  CAS  Google Scholar 

  • Yamaguchi N., Marczinski T. J. und Ling G. M.: The effects of electrical and chemical stimulation of the preoptic region and some non-spezific thalamic nuclei in unrestrained, waking animals. EEG clin. Neurophysiol. 15, 154 (1963).

    Article  Google Scholar 

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Authors and Affiliations

  1. Basel, Schweiz

    Marcel Monnier

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  1. Marcel Monnier
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  1. Universitäts-Nervenklinik und -Poliklinik, Würzburg, Füchslein-Str. 15, Deutschland

    Uroš J. Jovanović (Priv.-Dozent) (Priv.-Dozent)

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© 1969 Johann Ambrosius Barth München

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Monnier, M. (1969). Biochemische, pharmakologische und humorale Aspekte des Schlaf-Wachseins. In: Jovanović, U.J. (eds) Der Schlaf. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86165-9_6

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  • DOI: https://doi.org/10.1007/978-3-642-86165-9_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-86166-6

  • Online ISBN: 978-3-642-86165-9

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