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Ist das signalgemittelte EKG zur Kontrolle einer antiarrhythmischen Therapie geeignet?

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Medikamentöse Behandlung des Postinfarktpatienten nach CAST

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Zusammenfassung

Die nichtinvasive Kontrolle einer antiarrhythmischen Therapie wird anhand der Reduktion spontaner Arrhythmien im Langzeit-EKG durchgeführt. Probleme dieses Verfahrens liegen unter anderem in der ausgeprägten Spontanvariabilität der ventrikulären Arrhythmien und vor allem in dem fehlenden Nachweis, daß eine Reduktion dieser Ektopien den plötzlichen Herztod verhindert. Es wäre also von großem klinischen Nutzen, über eine weitere nichtinvasive Methode zur Einschätzung der Wirkung von Antiarrhythmika zu verfügen. Dabei bietet sich das Signalmittelungs-EKG an, da es mit der Beschreibung von Spätpotentialen den Nachweis von Zonen verzögerter Erregung ermöglicht, die eine Basis für kreisende Tachykardien darstellen können (9, 15, 16, 17, 35). Diese im Signalmittelungs-EKG erfaßbaren Spätpotentiale sind elektrische Signale, die nach Beendigung der normalen Kammererregung, also am Ende des QRS-Komplexes und in der folgenden ST-Strecke auftreten (2, 8, 35, 36), (Abb. 1).

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Authors and Affiliations

  1. I. Medizinische Klinik Klinikum rechts der Isar, Technischen Universität München, Ismaninger Straße 22, 8000, München 80, Germany

    Frau Priv.-Doz. Dr. med. Lieselotte Goedel-Meinen, M. Hofmann, G. Schmidt, P. Barthel, W. Baedeker & H. Blömer

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  1. Frau Priv.-Doz. Dr. med. Lieselotte Goedel-Meinen
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  2. M. Hofmann
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  3. G. Schmidt
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  4. P. Barthel
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  5. W. Baedeker
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  6. H. Blömer
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  1. I. Medizinische Klinik, Technischen Universität München Klinikum rechts der Isar, Ismaninger Straße 22, 8000, München 80, Germany

    Georg Schmidt

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© 1991 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt

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Goedel-Meinen, L., Hofmann, M., Schmidt, G., Barthel, P., Baedeker, W., Blömer, H. (1991). Ist das signalgemittelte EKG zur Kontrolle einer antiarrhythmischen Therapie geeignet?. In: Schmidt, G. (eds) Medikamentöse Behandlung des Postinfarktpatienten nach CAST. Steinkopff. https://doi.org/10.1007/978-3-642-85414-9_8

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  • DOI: https://doi.org/10.1007/978-3-642-85414-9_8

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-85415-6

  • Online ISBN: 978-3-642-85414-9

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