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Immunkomplexe fehlen an der mit Granulozyten infiltrierten subchondralen Pannus-Knorpel-Grenze bei der chronischen Polyarthritis

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Experimentelle Rheumatologie

Part of the book series: Der Rheumatismus ((2798,volume 45))

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Zusammenfassung

Bei der chronischen Polyarthritis (CP) wird der Oberflächenpannus gemeinhin als jenes Gewebe betrachtet, das den Gelenkknorpel zerstört. Dabei sollen nach Fassbender in einem nichtentzündlichen Prozeß unreif aussehende synoviale tumorartige Zellen („mesenchymoide Transformation“) für die Knorpelresorption verantwortlich sein (1,2). Untersuchungsbefunde anderer Autoren unterstreichen jedoch die entzündliche Natur des destruktiven Gelenkprozesses, da makrophagen- und fibroblastenartige Zellen (3, 4), Mastzellen (5, 6) und neutrophile Granulozyten (7-9) in der Grenzzone zwischen Knorpel und Pannus beschrieben werden.

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Author information

Authors and Affiliations

  1. Rheuma-Zentrum des Bayerischen Roten Kreuzes, 8403, Bad Abbach, Germany

    Priv.-Doz. Dr. med. H. Menninger (Chefarzt der I.-Medizinischen Klinik) & D. Wessinghage

  2. Universität Ulm, 8403, Bad Abbach, Germany

    W. Mohr

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  1. Priv.-Doz. Dr. med. H. Menninger
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  2. W. Mohr
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  3. D. Wessinghage
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Editor information

Editors and Affiliations

  1. Med. Zentrum für Orthopädie, Klinikum der Justus-Liebig-Universität, Paul-Meimberg-Str. 3, 6300, Gießen, Germany

    U. Weber

  2. Klinik für physikalische Medizin, Balneologie und Rheumatologie der Universität Gießen, Ludwigstraße 37-39, 6350, Bad Nauheim, Germany

    K. L. Schmidt

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© 1986 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt

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Menninger, H., Mohr, W., Wessinghage, D. (1986). Immunkomplexe fehlen an der mit Granulozyten infiltrierten subchondralen Pannus-Knorpel-Grenze bei der chronischen Polyarthritis. In: Weber, U., Schmidt, K.L. (eds) Experimentelle Rheumatologie. Der Rheumatismus, vol 45. Steinkopff. https://doi.org/10.1007/978-3-642-85356-2_12

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  • DOI: https://doi.org/10.1007/978-3-642-85356-2_12

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-0690-9

  • Online ISBN: 978-3-642-85356-2

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