Metrical Aspects of Two-Center Hydrogen Bonds

Abstract

The donor and acceptor groups found in biological structures which form O — H ··· O bonds are given in Box 6.1. The C — OH ⋯ O hydrogen bonds are the primary intermolecular cohesive force between the carbohydrate molecules, water, and carboxylic acids. They occur extensively in the structures of cyclodextrins, polysaccharides, glycolipids, and glycoproteins. The O_WH ··· O bonds are important in the ices, in hydrated crystal structures, and in the hydration shell of all biological molecules.

Henceforth, crystal structure analyses of carbohydrates (class 45), amino acids (class 48), purines and pyrimidines (class 44) and nucleosides and nucleotides (class 47) are referenced by means of their Cambridge Crystallographic Data Base REFCODES. All other crystal structure analyses are referenced in the General Index.