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Muscle Intracellular Ions during Malnutrition and Refeeding

  • Chapter
Metabolic Support of the Critically Ill Patient

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 17))

Abstract

Consequences of protein-calorie malnutrition (PCM) have mostly been approached in terms of changes in body cell mass, or in body compartments as lean and fat masses. Such an approach exaggerates the relationship between tissue composition and tissue function. In addition, evidence of body compartment alterations does not provide any information about the pathophysiological consequences of such changes. For instance, does a reduction in muscle mass reduce the muscle performance in terms of power and endurance? In contrast, a function-oriented approach gives an overall appreciation of the integrity of a given mechanism which might be altered by malnutrition. Functions might be studied at different levels: a whole organism (i.e. heat production), an organ (i.e. muscle power), or an individual cell (i.e. membrane potential). At the cellular level, the relationship between ions content and membrane properties reflects that between PCM and cellular function.

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Authors
  1. C. Pichard
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  2. D. Slosman
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  3. A. G. Dulloo
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Editor information

Editors and Affiliations

  1. Laboratory for Surgical Metabolism, Brigham and Women’s Hospital, 75 Francis Street, Boston, Massachussetts, 02115, USA

    Douglas W. Wilmore

  2. L. Deloyers Laboratory for Experimental Surgery, Free University of Brussels, Avenue J. Wybran 40, 1070, Brussels, Belgium

    Yvon A. Carpentier

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© 1993 Springer-Verlag Berlin Heidelberg

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Pichard, C., Slosman, D., Dulloo, A.G. (1993). Muscle Intracellular Ions during Malnutrition and Refeeding. In: Wilmore, D.W., Carpentier, Y.A. (eds) Metabolic Support of the Critically Ill Patient. Update in Intensive Care and Emergency Medicine, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85011-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-85011-0_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85013-4

  • Online ISBN: 978-3-642-85011-0

  • eBook Packages: Springer Book Archive

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