Abstract
Fluorocarbons, which are often known as perfluorocarbons or perfluorochemicals (PFCs), are almost completely inert chemical substances with a very high solubility for the respiratory gases. They are currently under investigation as constituents of oxygen carrying plasma substitutes.
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References
Faithfull NS, Erdmann W, Fennema M, Kok A (in press) Effects of haemodilution with fluorocarbons or dextran on oxygen tensions in the acutely ischaemic myocardium. Brit J Anaesth
Faithfull NS, Fennema M, Erdmann W, Lapin R, Smith AR, van Alphen W, Essed CR, Trouwborst A (1985) Tissue oxygenation byfluorocarbons. Adv Exp Med Biol 180: 569–580
Smith AR, v Alphen W, Faithfull NS, Fennema M (1985) Limb Preservation in replantation surgery. J Plast Reconst Surg 75: 277–237
Virmani R, Fink LM, Gunther K, English D (1984) Effect of perfluorochemical blood substitutes on human neutrophil function. Transfusion 24: 343–347
Forman MB, Bingham S, Koppelman HA, Wehr C, Friesinger GC, Virmani R (1985) Reduction of infarct size with intracoronary perfluorochemical in a canine preparation of re-perfusion. Circulation 71: 1060–1068
Biro GP (1983) Fluorocarbon and dextran hemodilution in myocardial ischemia. Can J Surg 26: 163–168
Rude RE, Golgar D, Khuri SF (1982) Effects of intravenous fluorocarbons during and without oxygen enhancement on acute myocardial ischemic injury assessed by measurement of intramyocardial gas tensions. Am Heart J 103: 986–995
Golgar DH, Kloner RA, Muller J, De Boer LWJ, Braunwald E (1981) Fluorocarbons reduce myocardial ischemia after coronary occlusion. Science 211: 1439–1441
Peerless SJ, Nakamura R, Rodriguez-Salazar A (1985) Modification of cerebral ischemia with Fluosol. Stroke 16: 38–43
Mizoi K, Yoshimoto T, Suzuki J (1981) Experimental study of new cerebral protective substances–Functional recovery of severe, incomplete ischaemic brain lesions pretreated with mannitol and fluorocarbon emulsion. Acta Neurochirurgica 56: 157–166
Oda Y, Murata T, Uehida Y (1982) Clinical evaluation of artificial blood substitute (Fluosol-DA 20%) in patients with cerebral ischaemia. Neurol Surg 10: 637–644
Long DM (1982) Fluorocarbons and synthetic bloods: capabilities and future uses. In: Utely JR (ed) Pathophysiology and techniques of cardiopulmonary bypass. Voll I. Williams and Wilkins, Baltimore London, pp 12–23
Teicher BA, Rose CM (1984) Perfluorochemical emulsions can increase tumor radiosensitivity. Science 223: 934–936
Faithfull NS, King CE, Cain SM (in press) Critical oxygen delivery levels during haemorrhagic shock following haemodilution with dextran of fluorocarbons. Brit J Anaesth
Honda K, Motoki R, Hoshino S, Inoue H, Usuba A, Hamada O, Iwaya F, Ando M (1980) Use of perfluorochemical artificial blood ( Fluosol-DA) for perfusion of cadaveric kidneys for transplantation. Curr Ther Res 28: 309–318
Mitsuno T, Ohyanagi H, Yokoyama K (1984) Development of a perfluorochemical emulsion as a blood gas carrier. Artificial Organs 8: 25–33
Long DM, Higgins CB, Mattrey RF, Mitten RM, Multer FK (1982) Is there a time and place for radiopaque fluorocarbons. In: Banks RE (ed) Preparation, properties and industrial applications of organofluoride preparations. Ellis Horwood, Chichister. pp 139–156
Itaoka T, Wada J, Kei J, Nagara H (1982) An improved cardiovascular angiography with Fluosol-DA. In: Frey R, Breisbarth H, Stosseck K (eds) Oxygen carrying colloidal blood substitutes. Zuckschwerdt, Munich. pp 197–203
Howlett S. Dundas D, Sabiston D (1965) Fluid fluorocarbon as oxygenator in experimental extracorporeal circulation. Arch Surg 91: 643–654
Adachi S, Mori T, Kitamuta S. Miyamoto K, Murata H, Okuda A, Kawashima Y (1979) Cardiopulmonary bypass primed with 35% W/V/% PFC emulsion after removal of 75% of autologous blood. In: Proceedings of the IVth International Symposium on Perfluorochemical Blood Substitutes. Exerpta Medica, Amsterdam. pp 319–329
Kanter KR, Jaffin JH, Ehrlichman J, Flaherty JT, Gott VL, Gardner TJ (1981) Superiority of perfluorocarbon cardioplegia over blood or crystaloid cardioplegy. Circulation 64 (Suppl II): 75–80
Faithfull NS, Klein J, van der Zee H, Salt PJ (1984) Whole body oxygenation using intra-peritoneal perfusion with fluorocarbons. Brit J Anaesth 56: 867–872
Miller ML, Sinnett D, Clark LC (1980) Ultrastructure of peritoneal exudate cells stimulated in vivo by perfluorochemical emulsions. J Reticuloendothelial Soc 27: 105–118
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© 1986 Springer-Verlag Berlin Heidelberg
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Faithfull, N.S. (1986). Microcirculatory and Other Applications of Fluorocarbons. In: Vincent, J.L. (eds) 6th International Symposium on Intensive Care and Emergency Medicine. Update in Intensive Care and Emergency Medicine, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82801-0_51
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DOI: https://doi.org/10.1007/978-3-642-82801-0_51
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16508-8
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