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Regional Monitoring of Gut Mucosal Viability

  • Chapter
The Splanchnic Circulation

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 23))

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Abstract

It is increasingly evident that systemic measures of oxygen transport (TO2) and consumption (VO2) fail to provide the information necessary to reverse the disastrous consequences of multiple organ dysfunction. Perhaps our disillusion with these systemic parameters is the result of overly optimistic expectations that physiological principles of mass transport could be sufficiently sensitive to characterize the complex process of tissue oxygenation [1]. Systemic TO2, defined as the product of cardiac output and arterial O2 content, portrays the capacity of the cardiopulmonary system to oxygenate and transport blood to the major vessels. Systemic VO2 is a measure of the rate of oxygen uptake by perfused tissues, the bulk of which is used by the mitochondria to produce energy via oxidative phosphorylation. These systemic parameters, however, offer scant information on the aerobic energy balance of cells.

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Authors
  1. G. Gutierrez
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  2. R. A. Cabezas
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Editor information

Editors and Affiliations

  1. Dept. of Anesthesiology and Critical Care Medicine, University of Pittsburgh, 604 Scaife Hall, 15261, Pittsburgh, PA, USA

    Michael R. Pinsky

  2. Clinical Pharmacology and Critical Care Medicine, Cochin Port-Royal University Hospital, 27 rue du Faubourg St. Jaques, F-75679, Paris, France

    Jean-Francois Dhainaut

  3. Servei des Medicina Intensiva Parc Tauli, Consorci Hospitalari Parc Tauli, E-08208, Sabadell, Spain

    Antonio Artigas

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© 1995 Springer-Verlag Berlin Heidelberg

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Gutierrez, G., Cabezas, R.A. (1995). Regional Monitoring of Gut Mucosal Viability. In: Pinsky, M.R., Dhainaut, JF., Artigas, A. (eds) The Splanchnic Circulation. Update in Intensive Care and Emergency Medicine, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79715-6_9

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  • DOI: https://doi.org/10.1007/978-3-642-79715-6_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79717-0

  • Online ISBN: 978-3-642-79715-6

  • eBook Packages: Springer Book Archive

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