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Mineralienmetabolismus und Osteopathie nach Nierentransplantation

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Nierentransplantation

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Zusammenfassung

Veränderungen im Metabolismus von Kalzium, Phosphat, Parathormon (PTH) und Vitamin D sind nach Nierentransplantation häufig (17). Die renale Osteodystrophie des Dialysepatienten, welche durch den sekundären Hyperparathyreoidismus und den Mangel an aktivem 1,25(OH)2 Vitamin D3 entsteht, wird durch ein funktionelles Transplantat zu einem gewissen Grad korrigiert (2). Auch die Aluminium-induzierte „low-turnover“ Knochenerkrankung wird durch die Transplantation verbessert, da Aluminium durch das gut funktionierende Transplantat sehr effizient aus dem Körper eliminiert wird. Auch das für die Dialyseassoziierte Amyloidose verantwortliche β2-Mikroglobulin wird durch ein gut funktionierendes Transplantat gut ausgeschieden, weshalb weitere Amyloidose- ablagerungen vermieden werden können. In diesem Kapitel werden die Mineralien- und Knochenveränderungen, auf welche nach der Transplantation geachtet werden muß, beschrieben.

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Authors and Affiliations

  1. Departement für innere Medizin Abt. für Nephrologie, Universitätsspital Zürich, Rämistraße 100, CH-8091, Zürich, Switzerland

    PD Dr. med. Rudolf Peter Wüthrich

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  1. PD Dr. med. Rudolf Peter Wüthrich
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© 1995 Springer-Verlag Berlin Heidelberg

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Wüthrich, R.P. (1995). Mineralienmetabolismus und Osteopathie nach Nierentransplantation. In: Nierentransplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79314-1_19

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  • DOI: https://doi.org/10.1007/978-3-642-79314-1_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79315-8

  • Online ISBN: 978-3-642-79314-1

  • eBook Packages: Springer Book Archive

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