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Evidence-Based Analysis of Nutrition Support in Sepsis

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Clinical Trials for the Treatment of Sepsis

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 19))

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Abstract

Nutrition support has become a standard of care in the management of intensive care unit (ICU) patients with the Systemic Inflammatory Response Syndrome (SIRS) with or without sepsis. Much of critical care therapy has been delivered on a physician preference basis. Worldwide, there is a major effort to shift to evidence-based medical decision-making. This effort requires the evaluation of medical literature that is based on objective methodologies for evaluating the quality of the data as well as the strength of the data in promoting evidence-based medical decision-making. This technology is available today.

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References

  1. Cook DJ (1994) Clinical trials in the treatment of sepsis: An evidence-based approach. See chapter by Cook in this book

    Google Scholar 

  2. Muller JM, Brenner U, Dienst C, Pichlmaier H (1982) Preoperative parenteral feeding in patients with gastrointestinal carcinoma. Lancet 1: 68–71

    Article  PubMed  CAS  Google Scholar 

  3. Mullen JL, Buzby GP, Matthews DC, Smale BF, Rosato EF (1980) Reduction of operative morbidity and mortality by combined preoperative and postoperative nutritional support. Ann of Surg 192: 604–613

    CAS  Google Scholar 

  4. Bellantone R, Doglietto GB, Bossola M, et al (1990) Preoperative parenteral nutrition in the high risk surgical patient. Am Soc Parent Ent Nutr 12: 195–197

    Article  Google Scholar 

  5. The Veterans Affairs Total Parenteral Nutrition Cooperative Study Group (1991) Perioperative total parenteral nutrition in surgical patients. N Engl J Med 325: 525–532

    Article  Google Scholar 

  6. Sandstrom R, Drott C, Aforvidsson B, et al (1993) The effect of postoperative TPN on outcome following major surgery evaluated in a randomized study. Ann Surg 217: 185–195

    Article  PubMed  CAS  Google Scholar 

  7. Detsky AS, Baker JP, O’Rourke K, Goel V (1987) Perioperative parenteral nutrition: A meta-analysis. Am Col Phys 107: 195–203

    CAS  Google Scholar 

  8. Moore FA, Moore EE, Jones TN, McCroskey BL, Peterson VM (1989) TEN versus TPN following major abdominal trauma — reduced septic morbidity. J Trauma 29: 916–923

    Article  PubMed  CAS  Google Scholar 

  9. Kudsk KA, Croce MA, Fabian TC, et al (1992) Enteral versus parenteral feeding. Ann Surg 215: 503–513

    Article  PubMed  CAS  Google Scholar 

  10. Moore FA, Feliciano DV, Andrassy RJ, et al (1992) Early enteral feeding, compared with parenteral, reduces postoperative septic complications. Ann Surg 215: 172–183

    Article  Google Scholar 

  11. Daly JM, Lieberman MD, Goldfine J, et al (1992) Enteral nutrition with supplemental arginine, RNA and omega-3 fatty acids in patients after operation. Immunologic, metabolic, and clinical outcome. Surg 112: 56–67

    CAS  Google Scholar 

  12. Bower RH, Lavin PT, Cerra FB, et al (1994) Early enteral administration of a formula supplemented with arginine, nucleotides and fish oils reduces length of stay of ICU patients: A randomized, prospective trial (in press)

    Google Scholar 

  13. Cerra FB, Cheung NK, Fischer JE, et al (1985) Disease-specific amino acid infusion (F080) in hepatic encephalopathy: A prospective, randomized, double-blind controlled trial. JPEN 9: 288–295

    Article  CAS  Google Scholar 

  14. Kuhl DA, Brown RO, Vehe KL, et al (1990) Use of selected visceral protein measurements in the comparison of branched-chain amino acids with standard amino acids in parenteral nutrition support of injured patients. Surg 107: 503–510

    CAS  Google Scholar 

  15. Jimenez Jimenez FJ, Leyba CO, Mendez SM, Perez MB, Garcia JM (1991) Prospective study on the efficacy of branched-chain amino acids in septic patients. JPEN 15: 252–261

    Article  CAS  Google Scholar 

  16. Bower RH, Muggia-Sullam M, Vallgren S, et al (1986) Branched-chain amino acid- enriched solutions in the septic patient: A randomized, prospective trial. Ann of Surg 203: 13–20

    Article  CAS  Google Scholar 

  17. Cerra FB, Mazuski J, Teasley K, et al (1983) Nitrogen retention in critically ill patients is proportional to the branched-chain amino acid load. Crit Car Med 11: 775–778

    Article  CAS  Google Scholar 

  18. Cerra FB, Upson D, Angelico R, et al (1982) Branched-chains support postoperative protein synthesis. Surg 82: 192–199

    Google Scholar 

  19. Cerra FB, Blackburn G, Hirsch J, Mullen K, Luther W (1987) The effect of stress level, amino acid formula and nitrogen dose on nitrogen retention in traumatic and septic stress. Ann Surg 205: 282–287

    Article  PubMed  CAS  Google Scholar 

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© 1995 Springer-Verlag Berlin Heidelberg

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Cerra, F.B. (1995). Evidence-Based Analysis of Nutrition Support in Sepsis. In: Vincent, JL., Sibbald, W.J. (eds) Clinical Trials for the Treatment of Sepsis. Update in Intensive Care and Emergency Medicine, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79224-3_14

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  • DOI: https://doi.org/10.1007/978-3-642-79224-3_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79226-7

  • Online ISBN: 978-3-642-79224-3

  • eBook Packages: Springer Book Archive

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