Abstract
Regeneration of peripheral nerve fibers following various lesions (see Sunder-land 1978) and restitution of peripheral nerve structure after severance of a nerve are followed by a number of changes. These are considered below.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Bardenheuer E (1908) Behandlung der Nerven bei Amputationen zur Verhütung der Amputationsneurome und zur Heilung der bestehenden Neurome durch die sogenannte Neurinkampsis. Dtsch Z Chir 96:126–135.
Beuche W, Friede RL (1985) A new approach toward analyzing peripheral nerve fiber populations. II. Foreshortening of regenerated internodes corresponds to reduced sheath thickness. J Neuropathol Exp Neurol 44:73–84.
Bohl J, Wallenfang T, von Bardeleben U, Schröder JM (1981) Kapselveränderungen an experimentell denervierten Muskelspindeln. In: Fortschritte der Myologie, Bd VI. Gutenbergdruckerei; Freiburg i. Br. 199–209.
Bunge MB, SanesJR, Wood PM, Tynan LB, Bates ML (1987) The cellular source of perineurium determined with a retroviral marker. Abstract, p. 79 8th Meeting of the Lake Couchiching Peripheral Nerve Study Group, Orsillia, Ontario, Canada, August 24–27, 1987.
Dieler R, Schröder JM (1990) Abnormal sensory and motor reinnervations of rat muscle spindles following nerve transection and suture. Acta Neuropathol (Berl): in press.
Dyck PJ, Lais AC, Karnes JL, Sparks M, Hunder H, Low PA, Windebank AJ (1981) Permanent axotomy, a model of axonal atrophy and secondary segmentai demyelination and remyelination. Ann Neurol 9:575–583.
Friede RL, Bischhausen R (1980) The precise geometry of large internodes. J Neurol Sci 48:367–381.
Guttmann L, Medawar PB (1942) The chemical inhibition of fibre regeneration and neuroma formation in peripheral nerves. J Neurol Psychiat 5:130–141.
Hiller F (1951) Nerve regeneration in grafts. J Neuropathol Clin Neurol 1:5–25.
Kawamura Y, Dyck PJ (1981) Permanent axotomy by amputation results in loss of motor neurons in man. J Neuropathol Exp Neurol 40:658–666.
Samii M (1981) Centrocentral anastomosis of peripheral nerves: A neurosurgical treatment of amputation neuromas. In: Siegfried J, Zimmermann M (eds) Phantom and Stump Pain. Springer, Berlin Heidelberg New York, 123–125.
Schröder JM (1972) Altered ratio between axon diameter and myelin sheath thickness in regenerated nerve fibers. Brain Res 45:49–65.
Schröder JM (1974) Two-dimensional reconstruction of Schwann cell changes following remyelination of regenerated nerve fibers. In: Hausmanova-Petrusewicz I, Jedrzejowska H (eds) Proceedings of the symposium on structure and function of normal and diseased muscle and peripheral nerve, in Kazimierz upon Vistula, Poland, May 18–20. Polish Medical Publ, pp 299-304.
Schröder JM (1975) Quantitative evaluation of regenerated nerve fibers. In: Kunze K, Desmedt JE (eds) Studies on neuromuscular diseases. Proceedings of the international Symposium on quantitative methods of investigations in the clinic of neuromuscular diseases. Gießen, April 8–10, 1973. Karger, Basel, pp 206–210.
Schröder JM (1985) Degeneration und Regeneration nach Plexus-brachialis-Verletzungen. In: Hase U, Reulen H-J (Hrsg) Läsionen des Plexus brachialis. De Gruyter, Berlin New York, 65–70.
Schröder JM (1987) Pathomorphologie der peripheren Nerven. In: Neundörfer (Hrsg.) Polyneuritiden und Polyneuropathien. In: Neundörfer B, Schirmig K, Soyka D (Hrsg) Praktische Neurologie, Bd 2 Edition Medizin VCH, Weinheim, 11–104.
Schröder JM, Müller E (1982) Fine structural morphometric evaluation of secondary myelin changes in retrograde axonal atrophy. Abstract. Arch. Suisses de Neurologie, Neurochirurgie et de Psychiatrie 131:254.
Schröder JM, Seiffert KE (1970) Die Feinstruktur der neuromatösen Neurotisation von Nerventransplantaten. Virch Arch Abt B Zellpath 5:219–235.
Schröder JM, Seiffert KW (1972) Untersuchungen zur homologen Nerventransplantation. Morphologische Ergebnisse. Zbl Neurochir 53:103–118.
Schröder JM, Kemme PT, Scholz L (1979) The fine structure of denervated and reinnervated muscle spindles: morphometric study of intrafusal muscle fibers. Acta neuropathol (Berl) 46:95–106.
Schröder JM, Bohl J, von Bardeleben U (1988) Changes of the ratio between myelin thickness and axon diameter in human developing sural, femoral, ulnar, facial and trochlear nerves. Acta Neuropathol (Berl) 76:471–483.
Smith KJ, Blakemore WF, Murray JA, Patterson RC (1982) Internodal myelin volume and axon surface area. J Neurol Sci 55:231–245.
Sunderland S (1978) Nerves and nerve injuries. 2nd edn. Churchill Livingstone, Edinburgh London New York, p 1046.
Wall PD, Devor M (1978) Physiology of sensation after peripheral nerve injury, regeneration, and neuroma formation. In: Waxmann SG (ed) Physiology and pathobiology of axons. Raven Press, New York, pp 377–388.
Weis J, Schröder JM (1989a) Differential effects of nerve, muscle, and fat tissue on regenerating nerve fibers in vivo. Muscle&Nerve 12:723–734.
Weis J, Schröder JM (1989b) The influence of fat tissue on neuroma formation. J Neurosurg 71:588–593.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Schröder, J.M. (1990). Pathomorphology of Regenerating Peripheral Nerves. In: Samii, M. (eds) Peripheral Nerve Lesions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75611-5_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-75611-5_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-75613-9
Online ISBN: 978-3-642-75611-5
eBook Packages: Springer Book Archive