Abstract
Molecular diffusion through polymers and synthetic membranes is an effective, simple and yet reliable means of attaining the controlled release of a variety of active agents. The principal devices utilizing this phenomenon are of the reservoir and monolithic types. In a reservoir device, the active agent is contained within the rate-controlling membrane, while in a monolithic device, the active agent is homogeneously dissolved or dispersed throughout the polymer matrix.
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Fan, Lt., Singh, S.K. (1989). Diffusion-Controlled Release. In: Controlled Release. Polymers, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74507-2_2
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