Abstract
It is well established in double-blind controlled studies that travelers’ diarrhea to a great extent can be prevented by prophylactic intake of antimicrobial chemotherapeutics [1, 2, 4]. Doxycycline; the combination of sulfamethoxazole/trimethoprim and trimethoprim alone; mecillinam; and recently norfloxacin and ciprofloxacin have shown protection rates of 60%–95%. However, the use of these agents may cause adverse reactions and may lead to emergence of resistant strains of enteric pathogens.
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Black FT, Gaarslev K, Ørskov F, Ørskov J, Stenderup A, Stenderup J, Christensen O (1983) Mecillinam, a new prophlactic for travelers’ diarrhoea. Scand J Infect Dis 15:189–193
DuPont HL, Ericsson CD, Johnson PC, Cabada FJ (1986) Antimicrobial agents in the prevention of travelers’ diarrhea. Rev Infect Dis [Suppl 2]8:167–171
DuPont HL, Ericsson CD, Johnson PC, Bilsura JAM, DuPont MW, Cabada FJ (1987) Prevention of travelers’ diarrhea by the tablet formulation of bismuth subsalicylate. JAMA 257:1347–1350
Sack RB (1986) Antimicrobial prophylaxis of travelers’ diarrhea: a selected summary. Rev Infect Dis [Suppl 2]8:160–166
Steffen R, Heusser R, DuPont HL (1986) Prevention of travelers’ diarrhea by nonantibiotic drugs. Rev Infect Dis [Suppl 2]8:151–159
Wiström J, Norrby SR, Burman LG, Lundholm R, Jellheden B, Englund G (1987) Norfloxacin versus placebo for prophylaxis against travelers’ diarrhoea. J Antimi-crob Chemother 20:563–574
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© 1989 Springer-Verlag Berlin Heidelberg
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Black, F.T., Andersen, P.L., Ørskov, J., Ørskov, F., Gaarslev, K., Laulund, S. (1989). Prophylactic Efficacy of Lactobacilli on Traveler’s Diarrhea. In: Steffen, R., Lobel, H., Haworth, J., Bradley, D.J. (eds) Travel Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73772-5_70
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DOI: https://doi.org/10.1007/978-3-642-73772-5_70
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