Abstract
In the treatment of bacterial infection with antibiotics, drug levels in tissues at the site of infection may be below the minimal inhibitory concentration (MIC) for the infecting organism [1, 2]. Exposure of bacteria to sub-MIC antibacterial drugs can result in alterations in bacterial morphology [3–5] and proliferation [6, 7] as well as changes in sensitivity of the organisms to serum [8, 9].
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Mandell, L.A., Afnan, M. (1989). Interactions Among Subinhibitory Antibiotics, Aerobic Gram-negative Rods, and Human Polymorphonuclear Neutrophils. In: Gillissen, G., Opferkuch, W., Peters, G., Pulverer, G. (eds) The Influence of Antibiotics on the Host-Parasite Relationship III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73653-7_19
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DOI: https://doi.org/10.1007/978-3-642-73653-7_19
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