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Immunity and Infections in the Neonate

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Immunology of the Neonate

Abstract

Bacterial infection of the newborn is a common problem that causes significant morbidity and mortality for the host. The overall risk of the more common types of neonatal bacterial infection - sepsis and meningitis - ranges from 3 to 6/1000 live births in the United States. Approximately 20%-50% of infected infants die of the illness, and for those who are treated successfully for meningeal infection, neurological sequelae are found in about one-half. Although a number of organisms have been linked etiologically with sepsis and meningitis neonatorum, 60% or more of these infections are primarily due to three pathogens, group B streptococcus (GBS), E. Coli, and L. Monocytogenes.

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Author information

Authors and Affiliations

  1. Departments of Pediatrics and Microbiology, and The International Center for Interdisciplinary Studies of Immunology, Georgetown University School of Medicine, Washington, D.C., USA

    Joseph A. Bellanti & Barbara J. Zeligs

Authors
  1. Joseph A. Bellanti
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  2. Barbara J. Zeligs
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Editor information

Editors and Affiliations

  1. Clinica Pediatrics, Universitá di Pavia, I-27100, Pavia, Italy

    G. Roberto Burgio

  2. Institute of Clinical Microbiology, University of Götebôrg, Guldhedsgatan 10, S-413 46, Göteborg, Sweden

    Lars Åke Hanson

  3. Clinica Pediatrica Ospedale dei Bambini, University of Brescia, Via del Medolo 2, I-25100, Brescia, Italy

    Alberto G. Ugazio

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© 1987 Springer-Verlag Berlin Heidelberg

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Bellanti, J.A., Zeligs, B.J. (1987). Immunity and Infections in the Neonate. In: Burgio, G.R., Hanson, L.Å., Ugazio, A.G. (eds) Immunology of the Neonate. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71094-0_15

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  • DOI: https://doi.org/10.1007/978-3-642-71094-0_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71096-4

  • Online ISBN: 978-3-642-71094-0

  • eBook Packages: Springer Book Archive

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