Skip to main content

Observations on Patients Allegedly Allergic to Local Anesthetic Drugs

  • Chapter
Neue Aspekte in der Regionalanaesthesie 3

Abstract

Not uncommonly, when patients develop an untoward response during an operative or dental procedure under local anesthesia, it is the local anesthetic agent that appears to be the culprit and, from there on, patients are “labelled” as allergic to that specific drug or, worse yet, to all “caine” drugs [1–3]. This motivated us to investigate several approaches for the purpose of defining the type of untoward reaction suffered by the patient and to attempt to establish whether, in fact, an allergic response had taken place. In our study we tested with various methods and drugs, as well as confirming the patients’ acceptability and tolerance of the nonreactive drugs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Rood JP (1973) A case of lignocaine sensitivity. Br Dent J 135: 411–412

    Article  PubMed  CAS  Google Scholar 

  2. Goransson K (1976) Hypersensitivity to priloeaine. Dermatologica 152: 158–160

    Article  PubMed  CAS  Google Scholar 

  3. Selden HM (1967) Reactions to local anesthetics. J Mich Dent Assoc 49: 41

    Google Scholar 

  4. Aldrete JA, Johnson DA (1970) Evaluation of intracutaneous testing for investigation of allergy to local anesthetic. Anesth Analg 49: 173–183

    PubMed  CAS  Google Scholar 

  5. Aldrete JA (1973) Reactions to local anesthetic drugs. In: Frazier CA (ed) Allergy and dentistry. Thomas, Springfield

    Google Scholar 

  6. Kahn G, Aldrete JA, Ryan SC (1971) Dermic sensitivity to preservatives and local anesthetics, comparison of immediate and delayed hypersensitivity. Ann Allerg 29: 480

    PubMed  CAS  Google Scholar 

  7. Levine RR (1978) Pharmacology: drug actions and reactions, 2nd ed. Little, Brown, Boston

    Google Scholar 

  8. Aldrete JA, Usubiaga LE (1979) New concepts for toxicity for local anesthetic agents. Reg Anesth 4 (3): 6–11

    Google Scholar 

  9. Verrill PJ (1975) Adverse reactions to local anaesthetics and vasoconstrictor drugs. Practitioner 214: 380–387

    PubMed  CAS  Google Scholar 

  10. Hitschmann OB, Leider M, Baer RL (1950) Dermatitis due to the procaine fraction of procaine penicillin. J Invest Dermatol 15: 165–166

    PubMed  CAS  Google Scholar 

  11. Aldrete JA, Johnson DA (1969) Allergy to local anesthetics. JAMA 207: 356–357

    Article  PubMed  CAS  Google Scholar 

  12. Giovannitti JA, Bennett CR (1979) Assessment of allergy to local anesthetics. J Am Dent Assoc 98: 701–706

    PubMed  CAS  Google Scholar 

  13. Lederman DA, Freedman PD, Kerpel SM, Lumerman H (1980) An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases. Oral Surg 49: 28–33

    Article  PubMed  CAS  Google Scholar 

  14. Sabbah A (1978) A study of allergy to local anesthetics using the lymphoblast transformation test. Ann Anesthesiol Fr 17: 281–284

    Google Scholar 

  15. Aldrete J A, O’Higgins JW (1971) Evaluation of patients with history of allergy to local anesthetic drugs. South Med J 64: 1118–1121

    Article  PubMed  CAS  Google Scholar 

  16. Sidon MA, Aldrete JA (1971) A patient with multiple allergies: what anesthetic to use. J Am Dent Assoc 82: 366–368

    PubMed  CAS  Google Scholar 

  17. Arora S, Aldrete JA (1976) Investigation of possible allergy to local anesthetic drugs, correlation of intradermal with intramuscular injections. Anesth Rev 2: 13–16

    Google Scholar 

  18. Ravindranathan N (1975) Allergic reaction to lignocaine. A case report. Br Dent J 138: 101–102

    Article  PubMed  CAS  Google Scholar 

  19. Bateman PP (1974) Multiple allergy to local anaesthetics including priloeaine. Med J Aust 2: 449–450

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Aldrete, J.A. (1984). Observations on Patients Allegedly Allergic to Local Anesthetic Drugs. In: Wüst, H.J., Zindler, M., d’Arcy Stanton-Hicks, M. (eds) Neue Aspekte in der Regionalanaesthesie 3. Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine, vol 158. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69453-0_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69453-0_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-13023-9

  • Online ISBN: 978-3-642-69453-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics