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Nucleic Acid Hybridization for the Detection of Viral Genomes

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New Developments in Diagnostic Virology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 104))

Abstract

Single-stranded nucleic acids can form stable duplexes if they encounter complementary sequences under appropriate conditions. This reaction is called hybridization and has been extensively used during the past 15 years to explore the structure and expression of cellular and viral genes. Particularly with the advance of molecular cloning, hybridization with specific probes has made it possible to isolate and study individual genes from genomic libraries and has thus contributed significantly to our understanding of eukaryotic gene organization.

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Author information

Authors and Affiliations

  1. Institut für Virologie, Zentrum für Hygiene der Universität Freiburg, Hermann-Herder-Str. 11, 78 Freiburg, Federal Republic of Germany

    Georg W. Bornkamm & Lutz Gissmann

  2. Faculté de Médicine Alexis Carrel, Laboratoire d’Epidemiologie et Immunovirologie des Tumeurs, Lyon, Cedex 2, France

    Claude Desgranges

Authors
  1. Georg W. Bornkamm
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  2. Claude Desgranges
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  3. Lutz Gissmann
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Editor information

Editors and Affiliations

  1. Institut für Medizinische Mikrobiologie, Infektions- und Seuchenmedizin, Veterinärstr. 13, 8000, München 22, Germany

    Peter A. Bachmann

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© 1983 Springer-Verlag Berlin Heidelberg

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Bornkamm, G.W., Desgranges, C., Gissmann, L. (1983). Nucleic Acid Hybridization for the Detection of Viral Genomes. In: Bachmann, P.A. (eds) New Developments in Diagnostic Virology. Current Topics in Microbiology and Immunology, vol 104. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68949-9_18

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  • DOI: https://doi.org/10.1007/978-3-642-68949-9_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68951-2

  • Online ISBN: 978-3-642-68949-9

  • eBook Packages: Springer Book Archive

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