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Synthesis, Integration, and Transcription of the Retroviral Provirus

  • Chapter
Retroviruses 1

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 103))

Abstract

The RNA genome of a retrovirus is copied into DNA by the viral enzyme, RNA-dependent DNA polymerase, and the DNA copy of the retrovirus genome is inserted into one of the host’s chromosomes. This DNA copy, called a provirus, is transcribed into RNA by host enzymes, giving rise to both viral genomic RNA and viral messenger RNA.

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  1. Cold Spring Harbor Laboratory, P.O. Box 100, Cold Spring Harbor, New York, 11724, USA

    Stephen H. Hughes

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  1. Dept. of Microbiology, University of Southern California, School of Medicine, 2011 Zonal Avenue HMR 401, 90033, Los Angeles, California, USA

    P. K. Vogt

  2. The Wistar Institute, 36th Street at Spruce, 19104, Philadelphia, PA, USA

    Hilary Koprowski

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Hughes, S.H. (1983). Synthesis, Integration, and Transcription of the Retroviral Provirus. In: Vogt, P.K., Koprowski, H. (eds) Retroviruses 1. Current Topics in Microbiology and Immunology, vol 103. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68943-7_2

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  • DOI: https://doi.org/10.1007/978-3-642-68943-7_2

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